Lineage for d4xx7a_ (4xx7 A:)

  1. Root: SCOPe 2.05
  2. 1886641Class d: Alpha and beta proteins (a+b) [53931] (381 folds)
  3. 1915130Fold d.80: Tautomerase/MIF [55330] (1 superfamily)
    (beta-alpha-beta)2; 2 layers: alpha/beta; mixed beta-sheet
    generally forms trimers with three closely packed beta-sheets
  4. 1915131Superfamily d.80.1: Tautomerase/MIF [55331] (7 families) (S)
  5. 1915295Family d.80.1.3: MIF-related [55339] (2 proteins)
    automatically mapped to Pfam PF01187
  6. 1915312Protein Microphage migration inhibition factor (MIF) [55340] (7 species)
    synonym: glycosylation-inhibiting factor (GIF)
  7. 1915318Species Human (Homo sapiens) [TaxId:9606] [55341] (59 PDB entries)
  8. 1915442Domain d4xx7a_: 4xx7 A: [277643]
    automated match to d1gifa_
    complexed with gol, ipa, so4; mutant

Details for d4xx7a_

PDB Entry: 4xx7 (more details), 1.77 Å

PDB Description: crystal structure of m2a mutant of human macrophage migration inhibitory factor
PDB Compounds: (A:) macrophage migration inhibitory factor

SCOPe Domain Sequences for d4xx7a_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4xx7a_ d.80.1.3 (A:) Microphage migration inhibition factor (MIF) {Human (Homo sapiens) [TaxId: 9606]}
pafivntnvprasvpdgflseltqqlaqatgkppqyiavhvvpdqlmafggssepcalcs
lhsigkiggaqnrsyskllcgllaerlrispdrvyinyydmnaanvgwnnstfa

SCOPe Domain Coordinates for d4xx7a_:

Click to download the PDB-style file with coordinates for d4xx7a_.
(The format of our PDB-style files is described here.)

Timeline for d4xx7a_: