Lineage for d4trua_ (4tru A:)

  1. Root: SCOPe 2.07
  2. 2530962Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2567390Fold d.80: Tautomerase/MIF [55330] (1 superfamily)
    (beta-alpha-beta)2; 2 layers: alpha/beta; mixed beta-sheet
    generally forms trimers with three closely packed beta-sheets
  4. 2567391Superfamily d.80.1: Tautomerase/MIF [55331] (7 families) (S)
  5. 2567647Family d.80.1.3: MIF-related [55339] (3 proteins)
    automatically mapped to Pfam PF01187
  6. 2567667Protein Microphage migration inhibition factor (MIF) [55340] (8 species)
    synonym: glycosylation-inhibiting factor (GIF)
  7. 2567673Species Human (Homo sapiens) [TaxId:9606] [55341] (94 PDB entries)
  8. 2567841Domain d4trua_: 4tru A: [277566]
    automated match to d3l5ua_
    complexed with gol, ipa, so4; mutant

Details for d4trua_

PDB Entry: 4tru (more details), 1.81 Å

PDB Description: crystal structure of q24a q25a mutant of human macrophage migration inhibitory factor
PDB Compounds: (A:) macrophage migration inhibitory factor

SCOPe Domain Sequences for d4trua_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4trua_ d.80.1.3 (A:) Microphage migration inhibition factor (MIF) {Human (Homo sapiens) [TaxId: 9606]}
pmfivntnvprasvpdgflseltaalaqatgkppqyiavhvvpdqlmafggssepcalcs
lhsigkiggaqnrsyskllcgllaerlrispdrvyinyydmnaanvgwnnstfa

SCOPe Domain Coordinates for d4trua_:

Click to download the PDB-style file with coordinates for d4trua_.
(The format of our PDB-style files is described here.)

Timeline for d4trua_: