SCOPe 2.08: Domain d4w9ya3: 4w9y A:594-750

Lineage for d4w9ya3 (4w9y A:594-750)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.48: N-cbl like [47667] (5 superfamilies)
   4 helices; bundle, left-handed twist; left-handed superhelix

4. Superfamily a.48.2: Transferrin receptor-like dimerisation domain [47672] (1 family)
   automatically mapped to Pfam PF04253

5. Family a.48.2.1: Transferrin receptor-like dimerisation domain [47673] (2 proteins)

6. Protein Glutamate carboxypeptidase II [140574] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [140575] (34 PDB entries)
   Uniprot Q04609 594-750

8. Domain d4w9ya3: 4w9y A:594-750 [277310]
   Other proteins in same PDB: d4w9ya1, d4w9ya2
   automated match to d2c6ca1
   complexed with 3k0, ca, cl, nag, zn

Details for d4w9ya3

PDB Entry: 4w9y, 1.64 Å

PDB Description: x-ray structure of human glutamate carboxypeptidase ii (gcpii) in complex with a glutamyl sulfamide inhibitor cjc47

PDB Compounds: (A:) glutamate carboxypeptidase 2

SCOPe Domain Sequences for d4w9ya3:

Sequence, based on SEQRES records:

>d4w9ya3 a.48.2.1 (A:594-750) Glutamate carboxypeptidase II {Human (Homo sapiens) [TaxId: 9606]}
pfdcrdyavvlrkyadkiysismkhpqemktysvsfdslfsavknfteiaskfserlqdf
dksnpivlrmmndqlmflerafidplglpdrpfyrhviyapsshnkyagesfpgiydalf
dieskvdpskawgevkrqiyvaaftvqaaaetlseva

Sequence, based on observed residues (ATOM records):

>d4w9ya3 a.48.2.1 (A:594-750) Glutamate carboxypeptidase II {Human (Homo sapiens) [TaxId: 9606]}
pfdcrdyavvlrkyadkiysismkhpqemktysvsfdslfsavknfteiaskfserlqdf
snpivlrmmndqlmflerafidplglpdrpfyrhviyapsshnkyagesfpgiydalfdi
eskvdpskawgevkrqiyvaaftvqaaaetlseva

Timeline for d4w9ya3:

• d4w9ya3 first appeared in SCOPe 2.05
  
• d4w9ya3 appears in SCOPe 2.07