Lineage for d4xaoa_ (4xao A:)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 2008476Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
    multihelical; 3 layers or orthogonally packed helices
  4. 2008477Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families) (S)
  5. 2008478Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 protein domains)
  6. 2009172Protein Pregnane x receptor, PXR [63624] (1 species)
  7. 2009173Species Human (Homo sapiens) [TaxId:9606] [63625] (16 PDB entries)
  8. 2009187Domain d4xaoa_: 4xao A: [277019]
    automated match to d1m13a_
    complexed with ipa, mpd

Details for d4xaoa_

PDB Entry: 4xao (more details), 2.58 Å

PDB Description: crystal structure of the hpxr-lbd obtained in presence of the pesticide trans-nonachlor
PDB Compounds: (A:) Nuclear receptor subfamily 1 group I member 2

SCOPe Domain Sequences for d4xaoa_:

Sequence, based on SEQRES records: (download)

>d4xaoa_ a.123.1.1 (A:) Pregnane x receptor, PXR {Human (Homo sapiens) [TaxId: 9606]}
glteeqrmmirelmdaqmktfdttfshfknfrlpgvlssgcelpeslqapsreeaakwsq
vrkdlcslkvslqlrgedgsvwnykppadsggkeifsllphmadmstymfkgiisfakvi
syfrdlpiedqisllkgaafelcqlrfntvfnaetgtwecgrlsycledtaggfqqllle
pmlkfhymlkklqlheeeyvlmqaislfspdrpgvlqhrvvdqlqeqfaitlksyiecnr
pqpahrflflkimamltelrsinaqhtqrllriqdihpfatplmqelfgitgs

Sequence, based on observed residues (ATOM records): (download)

>d4xaoa_ a.123.1.1 (A:) Pregnane x receptor, PXR {Human (Homo sapiens) [TaxId: 9606]}
glteeqrmmirelmdaqmktfdttfshfknfrlpgvsreeaakwsqvrkdlcslkvslql
rgedgsvwnykppadsggkeifsllphmadmstymfkgiisfakvisyfrdlpiedqisl
lkgaafelcqlrfntvfnaetgtwecgrlsycledfqqlllepmlkfhymlkklqlheee
yvlmqaislfspdrpgvlqhrvvdqlqeqfaitlksyiecnrpqpahrflflkimamlte
lrsinaqhtqrllriqdihpfatplmqelfgitgs

SCOPe Domain Coordinates for d4xaoa_:

Click to download the PDB-style file with coordinates for d4xaoa_.
(The format of our PDB-style files is described here.)

Timeline for d4xaoa_: