Lineage for d5cyic1 (5cyi C:1-296)

  1. Root: SCOPe 2.08
  2. 2923792Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. 2979545Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2979546Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2979693Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2980461Protein Cyclin-dependent PK, CDK2 [88855] (2 species)
    CMGC group; CDKs subfamily; serine/threonine kinase
  7. 2980462Species Human (Homo sapiens) [TaxId:9606] [88856] (417 PDB entries)
    Uniprot P24941
  8. 2980811Domain d5cyic1: 5cyi C:1-296 [276975]
    Other proteins in same PDB: d5cyia2, d5cyib1, d5cyib2, d5cyic2, d5cyid1, d5cyid2
    automated match to d1h1pa_
    complexed with 55s

Details for d5cyic1

PDB Entry: 5cyi (more details), 2 Å

PDB Description: cdk2/cyclin a covalent complex with 6-(cyclohexylmethoxy)-n-(4- (vinylsulfonyl)phenyl)-9h-purin-2-amine (nu6300)
PDB Compounds: (C:) cyclin-dependent kinase 2

SCOPe Domain Sequences for d5cyic1:

Sequence; same for both SEQRES and ATOM records: (download)

>d5cyic1 d.144.1.7 (C:1-296) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphl

SCOPe Domain Coordinates for d5cyic1:

Click to download the PDB-style file with coordinates for d5cyic1.
(The format of our PDB-style files is described here.)

Timeline for d5cyic1: