Lineage for d5bvfa_ (5bvf A:)

  1. Root: SCOPe 2.06
  2. 2170735Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2218047Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2218048Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2218179Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2219987Protein MAP kinase Erk2 [56134] (2 species)
    CMGC group; ERK/MAPK subfamily; serine/threonine kinase
  7. 2219988Species Human (Homo sapiens) [TaxId:9606] [56135] (31 PDB entries)
  8. 2219999Domain d5bvfa_: 5bvf A: [276655]
    automated match to d1erka_
    complexed with 4vj, so4

Details for d5bvfa_

PDB Entry: 5bvf (more details), 1.9 Å

PDB Description: tetrahydropyrrolo-diazepenones as inhibitors of erk2 kinase
PDB Compounds: (A:) Mitogen-activated protein kinase 1

SCOPe Domain Sequences for d5bvfa_:

Sequence, based on SEQRES records: (download)

>d5bvfa_ d.144.1.7 (A:) MAP kinase Erk2 {Human (Homo sapiens) [TaxId: 9606]}
agpemvrgqvfdvgprytnlsyigegaygmvcsaydnvnkvrvaikkispfehqtycqrt
lreikillrfrheniigindiiraptieqmkdvyivqdlmetdlykllktqhlsndhicy
flyqilrglkyihsanvlhrdlkpsnlllnttcdlkicdfglarvadpdhdhtgflteyv
atrwyrapeimlnskgytksidiwsvgcilaemlsnrpifpgkhyldqlnhilgilgsps
qedlnciinlkarnyllslphknkvpwnrlfpnadskaldlldkmltfnphkrieveqal
ahpyleqyydpsdepiaeapfkfdmelddlpkeklkelifeetarfqpgy

Sequence, based on observed residues (ATOM records): (download)

>d5bvfa_ d.144.1.7 (A:) MAP kinase Erk2 {Human (Homo sapiens) [TaxId: 9606]}
agpemvrgqvfdvgprytnlsyigegaygmvcsaydnvnkvrvaikkispfehqtycqrt
lreikillrfrheniigindiiraptieqmkdvyivqdlmetdlykllktqhlsndhicy
flyqilrglkyihsanvlhrdlkpsnlllnttcdlkicdfglarvrwyrapeimtksidi
wsvgcilaemlsnrpifpgkhyldqlnhilgilgspsqedlnciinlkarnyllslphkn
kvpwnrlfpnadskaldlldkmltfnphkrieveqalahpyleqyydpsdepiaeapfkf
dmelddlpkeklkelifeetarfqpgy

SCOPe Domain Coordinates for d5bvfa_:

Click to download the PDB-style file with coordinates for d5bvfa_.
(The format of our PDB-style files is described here.)

Timeline for d5bvfa_: