Lineage for d4xjta_ (4xjt A:)

  1. Root: SCOPe 2.07
  2. 2434694Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2463694Fold c.23: Flavodoxin-like [52171] (15 superfamilies)
    3 layers, a/b/a; parallel beta-sheet of 5 strand, order 21345
  4. 2466660Superfamily c.23.14: N-(deoxy)ribosyltransferase-like [52309] (4 families) (S)
    there are similar active site architectures as well as the catalytic mechanisms of functionally characterised members
  5. 2466704Family c.23.14.3: ADP ribosyl cyclase-like [56630] (3 proteins)
    contains extra N-terminal all-alpha subdomain
    automatically mapped to Pfam PF02267
  6. 2466705Protein ADP ribosyl cyclase [56631] (4 species)
  7. 2466730Species Human (Homo sapiens) [TaxId:9606] [159490] (45 PDB entries)
    Uniprot P28907 45-291
  8. 2466818Domain d4xjta_: 4xjt A: [276386]
    automated match to d1zvmc_
    complexed with 41z, na7

Details for d4xjta_

PDB Entry: 4xjt (more details), 2.6 Å

PDB Description: human cd38 complexed with inhibitor 2 [4-[(2,6-dimethylbenzyl)amino]- 2-methylquinoline-8-carboxamide]
PDB Compounds: (A:) ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1

SCOPe Domain Sequences for d4xjta_:

Sequence, based on SEQRES records: (download)

>d4xjta_ c.23.14.3 (A:) ADP ribosyl cyclase {Human (Homo sapiens) [TaxId: 9606]}
wrqqwsgpgttkrfpetvlarcvkyteihpemrhvdcqsvwdafkgafiskhpcditeed
yqplmklgtqtvpcnkillwsrikdlahqftqvqrdmftledtllgyladdltwcgefat
skinyqscpdwrkdcsnnpvsvfwktvsrrfaeaacdvvhvmldgsrskifdkdstfgsv
qvhnlqpekvqtleawvihggredsrdlcqdptikelesiiskrniqfsckniyrpdkfl
qcvkn

Sequence, based on observed residues (ATOM records): (download)

>d4xjta_ c.23.14.3 (A:) ADP ribosyl cyclase {Human (Homo sapiens) [TaxId: 9606]}
wrqqwsgpgttkrfpetvlarcvkyteihpemrhvdcqsvwdafkgafiskhpcditeed
yqplmklgtqtvpcnkillwsrikdlahqftqvqrdmftledtllgyladdltwcgefat
skinyqscpdwrkdcsnnpvsvfwktvsrrfaeaacdvvhvmldgsrskifdkdstfgsv
qvhnlqpekvqtleawvihgsrdlcqdptikelesiiskrniqfsckniyrpdkflqcvk
n

SCOPe Domain Coordinates for d4xjta_:

Click to download the PDB-style file with coordinates for d4xjta_.
(The format of our PDB-style files is described here.)

Timeline for d4xjta_: