SCOPe 2.05: Domain d4slia2: 4sli A:277-759

Lineage for d4slia2 (4sli A:277-759)

1. Root: SCOPe 2.05

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.68: 6-bladed beta-propeller [50938] (11 superfamilies)
   consists of six 4-stranded beta-sheet motifs; meander

4. Superfamily b.68.1: Sialidases [50939] (3 families)

5. Family b.68.1.1: Sialidases (neuraminidases) [50940] (10 proteins)

6. Protein Leech intramolecular trans-sialidase, C-terminal domain [50948] (1 species)
   contains incomplete beta-barrel subdomain inserted in the second blade

7. Species North american leech (Macrobdella decora) [TaxId:6405] [50949] (5 PDB entries)

8. Domain d4slia2: 4sli A:277-759 [27612]
   Other proteins in same PDB: d4slia1
   complexed with cnp

Details for d4slia2

PDB Entry: 4sli, 1.8 Å

PDB Description: leech intramolecular trans-sialidase complexed with 2-propenyl-neu5ac, an inactive substrate analogue

PDB Compounds: (A:) intramolecular trans-sialidase

SCOPe Domain Sequences for d4slia2:

Sequence; same for both SEQRES and ATOM records:

>d4slia2 b.68.1.1 (A:277-759) Leech intramolecular trans-sialidase, C-terminal domain {North american leech (Macrobdella decora) [TaxId: 6405]}
genifyagdvtesnyfripslltlstgtvisaadaryggthdskskiniafakstdggnt
wseptlplkfddyiaknidwprdsvgknvqiqgsasyidpvlledkltkriflfadlmpa
gigssnasvgsgfkevngkkylklrwhkdagraydytirekgviyndatnqptefrvdge
ynlyqhdtnltckqydynfsgnnliesktdvdvnmnifyknsvfkafptnylamrysdde
gaswsdldivssfkpevskflvvgpgigkqistgenagrllvplyskssaelgfmysddh
gdnwtyveadnltggataeaqivempdgslktylrtgsnciaevtsidggetwsdrvplq
gisttsygtqlsvinysqpidgkpaiilsspnatngrkngkiwiglvndtgntgidkysv
ewkysyavdtpqmgysysclaelpdgqvgllyekydswsrnelhlkdilkfekysiselt
gqa

Timeline for d4slia2:

• d4slia2 first appeared (with stable ids) in SCOP 1.55, called d4sli_2
  
• d4slia2 appears in SCOPe 2.04
  
• d4slia2 appears in SCOPe 2.06
  
• d4slia2 appears in the current release, SCOPe 2.08