Lineage for d5a0ae_ (5a0a E:)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2055629Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. 2055630Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families) (S)
  5. 2055877Family b.47.1.2: Eukaryotic proteases [50514] (49 protein domains)
  6. 2056282Protein Elastase [50536] (4 species)
  7. 2056285Species Human (Homo sapiens) [TaxId:9606] [50537] (12 PDB entries)
  8. 2056291Domain d5a0ae_: 5a0a E: [276105]
    automated match to d1ppfe_
    complexed with epe, jjs, nag

Details for d5a0ae_

PDB Entry: 5a0a (more details), 1.78 Å

PDB Description: crystal structure of human neutrophil elastase in complex with a dihydropyrimidone inhibitor
PDB Compounds: (E:) Neutrophil elastase

SCOPe Domain Sequences for d5a0ae_:

Sequence, based on SEQRES records: (download)

>d5a0ae_ b.47.1.2 (E:) Elastase {Human (Homo sapiens) [TaxId: 9606]}
ivggrrarphawpfmvslqlrgghfcgatliapnfvmsaahcvanvnvravrvvlgahnl
srreptrqvfavqrifengydpvnllndivilqlngsatinanvqvaqlpaqgrrlgngv
qclamgwgllgrnrgiasvlqelnvtvvtslcrrsnvctlvrgrqagvcfgdsgsplvcn
glihgiasfvrggcasglypdafapvaqfvnwidsiiq

Sequence, based on observed residues (ATOM records): (download)

>d5a0ae_ b.47.1.2 (E:) Elastase {Human (Homo sapiens) [TaxId: 9606]}
ivggrrarphawpfmvslqlrgghfcgatliapnfvmsaahcvanvnvravrvvlgahnl
srreptrqvfavqrifengydpvnllndivilqlngsatinanvqvaqlpaqgrrlgngv
qclamgwgllgrgiasvlqelnvtvvtslcrrsnvctlvrgrqagvcfgdsgsplvcngl
ihgiasfvrggcasglypdafapvaqfvnwidsiiq

SCOPe Domain Coordinates for d5a0ae_:

Click to download the PDB-style file with coordinates for d5a0ae_.
(The format of our PDB-style files is described here.)

Timeline for d5a0ae_: