SCOPe 2.08: Domain d5a0cb_: 5a0c B:

Lineage for d5a0cb_ (5a0c B:)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (49 proteins)

6. Protein Elastase [50536] (4 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50537] (15 PDB entries)

8. Domain d5a0cb_: 5a0c B: [276104]
   automated match to d1ppfe_
   complexed with jjv, mes, xpe

Details for d5a0cb_

PDB Entry: 5a0c, 2.1 Å

PDB Description: crystal structure of human neutrophil elastase in complex with a dihydropyrimidone inhibitor

PDB Compounds: (B:) Neutrophil elastase

SCOPe Domain Sequences for d5a0cb_:

Sequence; same for both SEQRES and ATOM records:

>d5a0cb_ b.47.1.2 (B:) Elastase {Human (Homo sapiens) [TaxId: 9606]}
ivggrrarphawpfmvslqlrgghfcgatliapnfvmsaahcvanvnvravrvvlgahnl
srreptrqvfavqrifengydpvnllndivilqlngsatinanvqvaqlpaqgrrlgngv
qclamgwgllgrnrgiasvlqelnvtvvtslcrrsnvctlvrgrqagvcfgdsgsplvcn
glihgiasfvrggcasglypdafapvaqfvnwidsiiq

Timeline for d5a0cb_:

• d5a0cb_ first appeared in SCOPe 2.05
  
• d5a0cb_ appears in SCOPe 2.07