SCOPe 2.08: Domain d4zo5a1: 4zo5 A:439-759

Lineage for d4zo5a1 (4zo5 A:439-759)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
   multihelical; consists of two different alpha-helical bundles

4. Superfamily a.211.1: HD-domain/PDEase-like [109604] (9 families)

5. Family a.211.1.0: automated matches [191566] (1 protein)
   not a true family

6. Protein automated matches [190983] (12 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188676] (139 PDB entries)

8. Domain d4zo5a1: 4zo5 A:439-759 [276090]
   Other proteins in same PDB: d4zo5a2, d4zo5b2
   automated match to d2ounb_
   complexed with 4px, 4q0, mg, zn

Details for d4zo5a1

PDB Entry: 4zo5, 2.5 Å

PDB Description: pde10 complexed with 4-isopropoxy-2-(2-(3-(4-methoxyphenyl)-4-oxo-3,4- dihydroquinazolin-2-yl)ethyl)isoindoline-1,3-dione

PDB Compounds: (A:) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A

SCOPe Domain Sequences for d4zo5a1:

Sequence; same for both SEQRES and ATOM records:

>d4zo5a1 a.211.1.0 (A:439-759) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sictseewqglmqftlpvrlckeielfhfdigpfenmwpgifvymvhrscgtscfelekl
crfimsvkknyrrvpyhnwkhavtvahcmyailqnnhtlftdlerkglliaclchdldhr
gfsnsylqkfdhplaalyststmeqhhfsqtvsilqleghnifstlssseyeqvleiirk
aiiatdlalyfgnrkqleemyqtgslnlnnqshrdrviglmmtacdlcsvtklwpvtklt
andiyaefwaegdemkklgiqpipmmdrdkkdevpqgqlgfynavaipcyttltqilppt
epllkacrdnlsqwekvirge

Timeline for d4zo5a1:

• d4zo5a1 first appeared in SCOPe 2.05, called d4zo5a_
  
• d4zo5a1 appears in SCOPe 2.07