SCOPe 2.08: Domain d4xlda1: 4xld A:203-477

Lineage for d4xlda1 (4xld A:203-477)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Peroxisome proliferator activated receptor gamma, PPAR-gamma [48524] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48525] (172 PDB entries)
   Uniprot P37231 232-505

8. Domain d4xlda1: 4xld A:203-477 [276045]
   Other proteins in same PDB: d4xlda2
   automated match to d3tkma_
   complexed with brl, fmt

Details for d4xlda1

PDB Entry: 4xld, 2.45 Å

PDB Description: crystal structure of the human pparg-lbd/rosiglitazone complex obtained by dry co-crystallization and in situ diffraction

PDB Compounds: (A:) Peroxisome proliferator-activated receptor gamma

SCOPe Domain Sequences for d4xlda1:

Sequence, based on SEQRES records:

>d4xlda1 a.123.1.1 (A:203-477) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
qlnpesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedki
kfkhitplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygv
heiiytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnaleldds
dlaifiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdl
rqivtehvqllqvikktetdmslhpllqeiykdly

Sequence, based on observed residues (ATOM records):

>d4xlda1 a.123.1.1 (A:203-477) Peroxisome proliferator activated receptor gamma, PPAR-gamma {Human (Homo sapiens) [TaxId: 9606]}
qlnpesadlralakhlydsyiksfpltkakarailtgktspfviydmnslmmgedkikfk
evairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytmlaslmn
kdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiaviilsg
drpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehvqllqv
ikktetdmslhpllqeiykdly

Timeline for d4xlda1:

• d4xlda1 first appeared in SCOPe 2.05, called d4xlda_
  
• d4xlda1 appears in SCOPe 2.07