SCOPe 2.08: Domain d4wrlb_: 4wrl B:

Lineage for d4wrlb_ (4wrl B:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.26: 4-helical cytokines [47265] (1 superfamily)
   core: 4 helices; bundle, closed; left-handed twist; 2 crossover connections

4. Superfamily a.26.1: 4-helical cytokines [47266] (4 families)
   there are two different topoisomers of this fold with different entanglements of the two crossover connections

5. Family a.26.1.2: Short-chain cytokines [47286] (14 proteins)

6. Protein automated matches [190501] (4 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187448] (21 PDB entries)

8. Domain d4wrlb_: 4wrl B: [276040]
   automated match to d3uf5a_
   complexed with nag, sia

Details for d4wrlb_

PDB Entry: 4wrl, 2.8 Å

PDB Description: structure of the human csf-1:csf-1r complex

PDB Compounds: (B:) macrophage colony-stimulating factor 1

SCOPe Domain Sequences for d4wrlb_:

Sequence, based on SEQRES records:

>d4wrlb_ a.26.1.2 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
evseycshmigsghlqslqrlidsqmetscqitfefvdqeqlkdpvcylkkafllvqdim
edtmrfrdntpnaiaivqlqelslrlkscftkdyeehdkacvrtfyetplqllekvknvf
netknlldkdwnifskncnnsfaec

Sequence, based on observed residues (ATOM records):

>d4wrlb_ a.26.1.2 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
evseycshmigsghlqslqrlidsqmetscqitfefvdqeqlkdpvcylkkafllvqdim
edtmrfrdntpnaiaivqlqelslrlkscftkdykacvrtfyetplqllekvknvfnetk
nlldkdwnifskncnnsfaec

Timeline for d4wrlb_:

• d4wrlb_ first appeared in SCOPe 2.05
  
• d4wrlb_ appears in SCOPe 2.07