SCOPe 2.08: Domain d5cr5b_: 5cr5 B:

Lineage for d5cr5b_ (5cr5 B:)

1. Root: SCOPe 2.08

2. Class e: Multi-domain proteins (alpha and beta) [56572] (74 folds)

3. Fold e.17: D-aminoacid aminotransferase-like PLP-dependent enzymes [56751] (1 superfamily)
   2 domains: (1) alpha+beta: beta3-alpha2-beta2; (2) alpha/beta, a part of its mixed sheet forms barrel: n=6, S=8

4. Superfamily e.17.1: D-aminoacid aminotransferase-like PLP-dependent enzymes [56752] (2 families)

5. Family e.17.1.1: D-aminoacid aminotransferase-like PLP-dependent enzymes [56753] (4 proteins)

6. Protein Branched-chain aminoacid aminotransferase [56757] (2 species)

7. Species Human (Homo sapiens), mitochondrial [TaxId:9606] [64508] (26 PDB entries)

8. Domain d5cr5b_: 5cr5 B: [275866]
   automated match to d2hhfa_
   complexed with cl, dms, edo, el1, plp

Details for d5cr5b_

PDB Entry: 5cr5, 1.61 Å

PDB Description: x-ray crystal structure at 1.61a resolution of human mitochondrial branched chain aminotransferase (bcatm) complexed with a biphenyl pyrrolidine ether compound and an internal aldimine linked plp cofactor.

PDB Compounds: (B:) Branched-chain-amino-acid aminotransferase, mitochondrial

SCOPe Domain Sequences for d5cr5b_:

Sequence, based on SEQRES records:

>d5cr5b_ e.17.1.1 (B:) Branched-chain aminoacid aminotransferase {Human (Homo sapiens), mitochondrial [TaxId: 9606]}
ssfkaadlqlemtqkphkkpgpgeplvfgktftdhmlmvewndkgwgqpriqpfqnltlh
passslhyslqlfegmkafkgkdqqvrlfrpwlnmdrmlrsamrlclpsfdklellecir
rlievdkdwvpdaagtslyvrpvlignepslgvsqptrallfvilcpvgayfpggsvtpv
slladpafirawvggvgnyklggnygptvlvqqealkrgceqvlwlygpdhqltevgtmn
ifvywthedgvlelvtpplngvilpgvvrqslldmaqtwgefrvvertitmkqllralee
grvrevfgsgtacqvcpvhrilykdrnlhiptmengpelilrfqkelkeiqygirahewm
fpv

Sequence, based on observed residues (ATOM records):

>d5cr5b_ e.17.1.1 (B:) Branched-chain aminoacid aminotransferase {Human (Homo sapiens), mitochondrial [TaxId: 9606]}
ssfkaadlqlemtqkphkkpglvfgktftdhmlmvewndkgwgqpriqpfqnltlhpass
slhyslqlfegmkafkgkdqqvrlfrpwlnmdrmlrsamrlclpsfdklellecirrlie
vdkdwvpdaagtslyvrpvlignepslgvsqptrallfvilcpvgayfpggsvtpvslla
dpafirawvggvgnyklggnygptvlvqqealkrgceqvlwlygpdhqltevgtmnifvy
wthedgvlelvtpplngvilpgvvrqslldmaqtwgefrvvertitmkqllraleegrvr
evfgsgtacqvcpvhrilykdrnlhiptmengpelilrfqkelkeiqygirahewmfpv

Timeline for d5cr5b_:

• d5cr5b_ first appeared in SCOPe 2.05
  
• d5cr5b_ appears in SCOPe 2.07