Lineage for d5a00a1 (5a00 A:662-796)

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2325363Fold a.41: Domain of poly(ADP-ribose) polymerase [47586] (1 superfamily)
    core: 4 helices: bundle; unusual topology
  4. 2325364Superfamily a.41.1: Domain of poly(ADP-ribose) polymerase [47587] (2 families) (S)
    duplication: consists of 2 helix-loop-helix structural repeats
    automatically mapped to Pfam PF02877
  5. 2325389Family a.41.1.0: automated matches [227223] (1 protein)
    not a true family
  6. 2325390Protein automated matches [226964] (2 species)
    not a true protein
  7. 2325394Species Human (Homo sapiens) [TaxId:9606] [225405] (61 PDB entries)
  8. 2325504Domain d5a00a1: 5a00 A:662-796 [275798]
    Other proteins in same PDB: d5a00a2
    automated match to d4gv2a1
    complexed with d7n, so4

Details for d5a00a1

PDB Entry: 5a00 (more details), 2.75 Å

PDB Description: structure of human parp1 catalytic domain bound to an isoindolinone inhibitor
PDB Compounds: (A:) Poly [ADP-ribose] polymerase 1

SCOPe Domain Sequences for d5a00a1:

Sequence, based on SEQRES records: (download)

>d5a00a1 a.41.1.0 (A:662-796) automated matches {Human (Homo sapiens) [TaxId: 9606]}

Sequence, based on observed residues (ATOM records): (download)

>d5a00a1 a.41.1.0 (A:662-796) automated matches {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d5a00a1:

Click to download the PDB-style file with coordinates for d5a00a1.
(The format of our PDB-style files is described here.)

Timeline for d5a00a1:

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