Lineage for d5ccca_ (5ccc A:)

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2903429Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest
  4. 2903430Superfamily c.71.1: Dihydrofolate reductase-like [53597] (3 families) (S)
  5. 2903431Family c.71.1.1: Dihydrofolate reductases [53598] (4 proteins)
  6. 2903517Protein Dihydrofolate reductase, prokaryotic type [53599] (9 species)
  7. 2903533Species Escherichia coli [TaxId:562] [53600] (86 PDB entries)
  8. 2903575Domain d5ccca_: 5ccc A: [275589]
    automated match to d1ddsa_
    complexed with ddf, nap

Details for d5ccca_

PDB Entry: 5ccc (more details), 1.5 Å

PDB Description: wild-type e.coli dihydrofolate reductase complexed with 5,10- dideazatetrahydrofolate and oxidized nicotinamide adenine dinucleotide phosphate
PDB Compounds: (A:) dihydrofolate reductase

SCOPe Domain Sequences for d5ccca_:

Sequence; same for both SEQRES and ATOM records: (download)

>d5ccca_ c.71.1.1 (A:) Dihydrofolate reductase, prokaryotic type {Escherichia coli [TaxId: 562]}
misliaalavdrvigmenampwnlpadlawfkrntlnkpvimgrhtwesigrplpgrkni
ilssqpgtddrvtwvksvdeaiaacgdvpeimvigggrvyeqflpkaqklylthidaeve
gdthfpdyepddwesvfsefhdadaqnshsycfeilerr

SCOPe Domain Coordinates for d5ccca_:

Click to download the PDB-style file with coordinates for d5ccca_.
(The format of our PDB-style files is described here.)

Timeline for d5ccca_: