SCOPe 2.08: Domain d5ccca_: 5ccc A:

Lineage for d5ccca_ (5ccc A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
   3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest

4. Superfamily c.71.1: Dihydrofolate reductase-like [53597] (3 families)

5. Family c.71.1.1: Dihydrofolate reductases [53598] (4 proteins)

6. Protein Dihydrofolate reductase, prokaryotic type [53599] (9 species)

7. Species Escherichia coli [TaxId:562] [53600] (86 PDB entries)

8. Domain d5ccca_: 5ccc A: [275589]
   automated match to d1ddsa_
   complexed with ddf, nap

Details for d5ccca_

PDB Entry: 5ccc, 1.5 Å

PDB Description: wild-type e.coli dihydrofolate reductase complexed with 5,10- dideazatetrahydrofolate and oxidized nicotinamide adenine dinucleotide phosphate

PDB Compounds: (A:) dihydrofolate reductase

SCOPe Domain Sequences for d5ccca_:

Sequence; same for both SEQRES and ATOM records:

>d5ccca_ c.71.1.1 (A:) Dihydrofolate reductase, prokaryotic type {Escherichia coli [TaxId: 562]}
misliaalavdrvigmenampwnlpadlawfkrntlnkpvimgrhtwesigrplpgrkni
ilssqpgtddrvtwvksvdeaiaacgdvpeimvigggrvyeqflpkaqklylthidaeve
gdthfpdyepddwesvfsefhdadaqnshsycfeilerr

Timeline for d5ccca_:

• d5ccca_ first appeared in SCOPe 2.05
  
• d5ccca_ appears in SCOPe 2.07