SCOPe 2.05: Domain d5bvoa_: 5bvo A:

Lineage for d5bvoa_ (5bvo A:)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (21 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (615 PDB entries)

8. Domain d5bvoa_: 5bvo A: [275586]
   automated match to d3zosb_
   complexed with 4ve, iod

Details for d5bvoa_

PDB Entry: 5bvo, 1.98 Å

PDB Description: fragment-based discovery of potent and selective ddr1/2 inhibitors

PDB Compounds: (A:) epithelial discoidin domain-containing receptor 1

SCOPe Domain Sequences for d5bvoa_:

Sequence, based on SEQRES records:

>d5bvoa_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dfprsrlrfkeklgegqfgevhlcevdspqdlvsldfplnvrkghpllvavkilrpdatk
narndflkevkimsrlkdpniirllgvcvqddplcmitdymengdlnqflsahqledkaa
egapgdgqaaqgptisypmllhvaaqiasgmrylatlnfvhrdlatrnclvgenftikia
dfgmsrnlyagdyyrvqgravlpirwmawecilmgkfttasdvwafgvtlwevlmlcraq
pfgqltdeqvienageffrdqgrqvylsrppacpqglyelmlrcwsreseqrppfsqlhr
flaedaln

Sequence, based on observed residues (ATOM records):

>d5bvoa_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dfprsrlrfkeklgefgevhlcevdshpllvavkilrpdatknarndflkevkimsrlkd
pniirllgvcvqddplcmitdymengdlnqflsahqledkptisypmllhvaaqiasgmr
ylatlnfvhrdlatrnclvgenftikiadfgmsrnlyagdyyrvqgravlpirwmaweci
lmgkfttasdvwafgvtlwevlmlcraqpfgqltdeqvienageffrdqgrqvylsrppa
cpqglyelmlrcwsreseqrppfsqlhrflaedaln

Timeline for d5bvoa_:

• d5bvoa_ is new in SCOPe 2.05-stable
  
• d5bvoa_ appears in SCOPe 2.06
  
• d5bvoa_ appears in the current release, SCOPe 2.08, called d5bvoa1