SCOPe 2.07: Domain d5a64a_: 5a64 A:

Lineage for d5a64a_ (5a64 A:)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.63: CYTH-like phosphatases [55153] (1 superfamily)
   duplication of beta-alpha-beta(3) motif: antiparallel beta sheet forms wide barrel (n=8, S=16) with a channel running through it

4. Superfamily d.63.1: CYTH-like phosphatases [55154] (3 families)

5. Family d.63.1.2: CYTH domain [118007] (5 proteins)
   Pfam PF01928

6. Protein Thiamine-triphosphatase (ThTPase) [160428] (2 species)

7. Species Mouse (Mus musculus) [TaxId:10090] [160429] (2 PDB entries)
   Uniprot Q8JZL3 2-224

8. Domain d5a64a_: 5a64 A: [275536]
   automated match to d2jmua1
   complexed with edo, pge, v4e

Details for d5a64a_

PDB Entry: 5a64, 2.1 Å

PDB Description: crystal structure of mouse thiamine triphosphatase in complex with thiamine triphosphate.

PDB Compounds: (A:) Thiamine triphosphatase

SCOPe Domain Sequences for d5a64a_:

Sequence, based on SEQRES records:

>d5a64a_ d.63.1.2 (A:) Thiamine-triphosphatase (ThTPase) {Mouse (Mus musculus) [TaxId: 10090]}
glieverkfapgpdteerlqelgatlehrvtfrdtyydtselslmlsdhwlrqregsgwe
lkcpgvtgvsgphneyvevtseaaivaqlfellgsgeqkpagvaavlgslklqevasfit
trsswklalsgahgqepqltidldsadfgyavgeveamvhekaevpaalekiitvssmlg
vpaqeeapaklmvylqrfrpldyqrlleaass

Sequence, based on observed residues (ATOM records):

>d5a64a_ d.63.1.2 (A:) Thiamine-triphosphatase (ThTPase) {Mouse (Mus musculus) [TaxId: 10090]}
glieverkfapgpdteerlqelgatlehrvtfrdtyydtselslmlsdhwlrqregsgwe
lkcpgvtgvsgphneyvevtseaaivaqlfellgsgeqkpagvaavlgslklqevasfit
trsswklaqltidldsadfgyavgeveamvhekaevpaalekiitvssmlgvpaqeeapa
klmvylqrfrpldyqrlleaass

Timeline for d5a64a_:

• d5a64a_ first appeared in SCOPe 2.05
  
• d5a64a_ appears in SCOPe 2.06
  
• d5a64a_ appears in the current release, SCOPe 2.08