Lineage for d4xecx_ (4xec X:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2136820Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest
  4. 2136821Superfamily c.71.1: Dihydrofolate reductase-like [53597] (3 families) (S)
  5. 2136822Family c.71.1.1: Dihydrofolate reductases [53598] (4 protein domains)
  6. 2136851Protein Dihydrofolate reductase, prokaryotic type [53599] (8 species)
  7. 2136984Species Staphylococcus aureus [TaxId:1280] [188976] (22 PDB entries)
  8. 2137005Domain d4xecx_: 4xec X: [275300]
    automated match to d3m08a_
    complexed with 06u, act, ndp

Details for d4xecx_

PDB Entry: 4xec (more details), 2.69 Å

PDB Description: staphylococcus aureus dihydrofolate reductase complexed with nadph and 6-ethyl-5-[(3r)-3-[3-methoxy-5-(pyridin-4-yl)phenyl]but-1-yn-1- yl]pyrimidine-2,4-diamine (ucp1061)
PDB Compounds: (X:) dihydrofolate reductase

SCOPe Domain Sequences for d4xecx_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4xecx_ c.71.1.1 (X:) Dihydrofolate reductase, prokaryotic type {Staphylococcus aureus [TaxId: 1280]}

SCOPe Domain Coordinates for d4xecx_:

Click to download the PDB-style file with coordinates for d4xecx_.
(The format of our PDB-style files is described here.)

Timeline for d4xecx_: