SCOPe 2.08: Domain d4uexa1: 4uex A:1-80

Lineage for d4uexa1 (4uex A:1-80)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.64: Saposin-like [47861] (2 superfamilies)
   5 helices; folded leaf, closed

4. Superfamily a.64.1: Saposin [47862] (5 families)
   Lipid-binding can promote conformational changes and oligomerisation in some members

5. Family a.64.1.1: NKL-like [47863] (4 proteins)

6. Protein automated matches [274940] (2 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [274941] (1 PDB entry)

8. Domain d4uexa1: 4uex A:1-80 [274942]
   Other proteins in same PDB: d4uexa2, d4uexb2
   automated match to d2doba_

Details for d4uexa1

PDB Entry: 4uex, 1.8 Å

PDB Description: structure of human saposin a at lysosomal ph

PDB Compounds: (A:) prosaposin

SCOPe Domain Sequences for d4uexa1:

Sequence; same for both SEQRES and ATOM records:

>d4uexa1 a.64.1.1 (A:1-80) automated matches {Human (Homo sapiens) [TaxId: 9606]}
slpcdickdvvtaagdmlkdnateeeilvylektcdwlpkpnmsasckeivdsylpvild
iikgemsrpgevcsalnlce

Timeline for d4uexa1:

• d4uexa1 first appeared in SCOPe 2.05, called d4uexa_
  
• d4uexa1 appears in SCOPe 2.07