Lineage for d4tu5x_ (4tu5 X:)

  1. Root: SCOPe 2.05
  2. 1815291Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 1871769Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest
  4. 1871770Superfamily c.71.1: Dihydrofolate reductase-like [53597] (3 families) (S)
  5. 1871771Family c.71.1.1: Dihydrofolate reductases [53598] (4 proteins)
  6. 1872124Protein automated matches [190514] (8 species)
    not a true protein
  7. 1872158Species Staphylococcus aureus [TaxId:273036] [274776] (1 PDB entry)
  8. 1872159Domain d4tu5x_: 4tu5 X: [274777]
    automated match to d3m08a_
    complexed with 06w, ndp

Details for d4tu5x_

PDB Entry: 4tu5 (more details), 2.16 Å

PDB Description: staphylococcus aureus dihydrofolate reductase complexed with nadph and 6-ethyl-5-[(3s)-3-[3-methoxy-5-(pyridin-4-yl)phenyl]but-1-yn-1- yl]pyrimidine-2,4-diamine (ucp1062)
PDB Compounds: (X:) dihydrofolate reductase

SCOPe Domain Sequences for d4tu5x_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4tu5x_ c.71.1.1 (X:) automated matches {Staphylococcus aureus [TaxId: 273036]}
tlsilvahdlqrvigfenqlpwhlpndlkhvkklstghtlvmgrktfesigkplpnrrnv
vltsdtsfnvegvdvihsiediyqlpghvfifggqtlfeemidkvddmyitviegkfrgd
tffppytfedwevassvegkldekntiphtflhlirk

SCOPe Domain Coordinates for d4tu5x_:

Click to download the PDB-style file with coordinates for d4tu5x_.
(The format of our PDB-style files is described here.)

Timeline for d4tu5x_: