SCOPe 2.05: Domain d5a5za_: 5a5z A:

Lineage for d5a5za_ (5a5z A:)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.157: Metallo-hydrolase/oxidoreductase [56280] (1 superfamily)
   duplication of beta(4)-alpha-beta-alpha motif; 4 layers a/b/b/a; mixed beta-sheets

4. Superfamily d.157.1: Metallo-hydrolase/oxidoreductase [56281] (15 families)

5. Family d.157.1.0: automated matches [191360] (1 protein)
   not a true family

6. Protein automated matches [190418] (15 species)
   not a true protein

7. Species Klebsiella pneumoniae [TaxId:573] [189718] (29 PDB entries)

8. Domain d5a5za_: 5a5z A: [274670]
   automated match to d4eyba_
   complexed with wjz, zn

Details for d5a5za_

PDB Entry: 5a5z, 2.6 Å

PDB Description: approved drugs containing thiols as inhibitors of metallo-beta- lactamases: strategy to combat multidrug-resistant bacteria

PDB Compounds: (A:) Beta-lactamase NDM-1

SCOPe Domain Sequences for d5a5za_:

Sequence; same for both SEQRES and ATOM records:

>d5a5za_ d.157.1.0 (A:) automated matches {Klebsiella pneumoniae [TaxId: 573]}
qqmetgdqrfgdlvfrqlapnvwqhtsyldmpgfgavasnglivrdggrvlvvdtawtdd
qtaqilnwikqeinlpvalavvthahqdkmggmdalhaagiatyanalsnqlapqegmva
aqhsltfaangwvepatapnfgplkvfypgpghtsdnitvgidgtdiafggclikdskak
slgnlgdadtehyaasarafgaafpkasmivmshsapdsraaithtarmadklrle

Timeline for d5a5za_:

• d5a5za_ is new in SCOPe 2.05-stable
  
• d5a5za_ is called d5a5za1 in SCOPe 2.06
  
• d5a5za_ appears in the current release, SCOPe 2.08, called d5a5za1