Lineage for d4zjic_ (4zji C:)

  1. Root: SCOPe 2.06
  2. 2170735Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2218047Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2218048Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2218179Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2220339Protein pak1 [56146] (1 species)
    OPK group; PAK/STE20 subfamily; serine/threonine kinase
  7. 2220340Species Human (Homo sapiens) [TaxId:9606] [56147] (19 PDB entries)
  8. 2220354Domain d4zjic_: 4zji C: [274406]
    automated match to d3q4za_
    complexed with 4oq, mg

Details for d4zjic_

PDB Entry: 4zji (more details), 1.99 Å

PDB Description: pak1 in complex with 2-chloro-5-ethyl-8-fluoro-11-(4-methylpiperazin- 1-yl)-dibenzodiazepine
PDB Compounds: (C:) Serine/threonine-protein kinase PAK 1

SCOPe Domain Sequences for d4zjic_:

Sequence, based on SEQRES records: (download)

>d4zjic_ d.144.1.7 (C:) pak1 {Human (Homo sapiens) [TaxId: 9606]}
deeileklrsivsvgdpkkkytrfekigqgasgtvytamdvatgqevaikqmnlqqqpkk
eliineilvmrenknpnivnyldsylvgdelwvvmeylaggsltdvvtetcmdegqiaav
creclqaleflhsnqvihrdiksdnillgmdgsvkltdfgfcaqitpeqskrstmvgtpy
wmapevvtrkaygpkvdiwslgimaiemiegeppylnenplralyliatngtpelqnpek
lsaifrdflnrclemdvekrgsakellqhqflkiakplssltpliaaakeat

Sequence, based on observed residues (ATOM records): (download)

>d4zjic_ d.144.1.7 (C:) pak1 {Human (Homo sapiens) [TaxId: 9606]}
deeileklrsivsvgdpkkkytrfekigqgasgtvytamdatgqevaikqmnkkeliine
ilvmrenknpnivnyldsylvgdelwvvmeylaggsltdvvtetcmdegqiaavcreclq
aleflhsnqvihrdiksdnillgmdgsvkltdfgfcaqskrstmvgtpywmapevvtrka
ygpkvdiwslgimaiemiegeppylnenplralyliatngtpelqnpeklsaifrdflnr
clemdvekrgsakellqhqflkiakplssltpliaaakeat

SCOPe Domain Coordinates for d4zjic_:

Click to download the PDB-style file with coordinates for d4zjic_.
(The format of our PDB-style files is described here.)

Timeline for d4zjic_: