SCOPe 2.08: Domain d4z78h1: 4z78 H:1-99

Lineage for d4z78h1 (4z78 H:1-99)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)

6. Protein beta2-microglobulin [88600] (7 species)

7. Species Human (Homo sapiens) [TaxId:9606] [88602] (480 PDB entries)
   Uniprot P61769 21-119 ! Uniprot P01884

8. Domain d4z78h1: 4z78 H:1-99 [274396]
   Other proteins in same PDB: d4z78a1, d4z78a2, d4z78a3, d4z78b2, d4z78d1, d4z78d2, d4z78d3, d4z78e2, d4z78g1, d4z78g2, d4z78g3, d4z78h2
   automated match to d1k5nb_
   complexed with edo, gol, so4

Details for d4z78h1

PDB Entry: 4z78, 2.3 Å

PDB Description: weak tcr binding to an unstable insulin epitope drives type 1 diabetes

PDB Compounds: (H:) Beta-2-microglobulin

SCOPe Domain Sequences for d4z78h1:

Sequence; same for both SEQRES and ATOM records:

>d4z78h1 b.1.1.2 (H:1-99) beta2-microglobulin {Human (Homo sapiens) [TaxId: 9606]}
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

Timeline for d4z78h1:

• d4z78h1 first appeared in SCOPe 2.05, called d4z78h_
  
• d4z78h1 appears in SCOPe 2.07