SCOPe 2.06: Domain d4wdib1: 4wdi B:1-99

Lineage for d4wdib1 (4wdi B:1-99)

1. Root: SCOPe 2.06

2. Class b: All beta proteins [48724] (177 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)

6. Protein beta2-microglobulin [88600] (6 species)

7. Species Human (Homo sapiens) [TaxId:9606] [88602] (424 PDB entries)
   Uniprot P61769 21-119 ! Uniprot P01884

8. Domain d4wdib1: 4wdi B:1-99 [274351]
   Other proteins in same PDB: d4wdia1, d4wdia2, d4wdia3, d4wdib2, d4wdid1, d4wdid2, d4wdid3, d4wdie2
   automated match to d1k5nb_
   complexed with edo, so4

Details for d4wdib1

PDB Entry: 4wdi, 2.31 Å

PDB Description: weak tcr binding to an unstable insulin epitope drives type 1 diabetes

PDB Compounds: (B:) Beta-2-microglobulin

SCOPe Domain Sequences for d4wdib1:

Sequence; same for both SEQRES and ATOM records:

>d4wdib1 b.1.1.2 (B:1-99) beta2-microglobulin {Human (Homo sapiens) [TaxId: 9606]}
iqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskdw
sfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm

Timeline for d4wdib1:

• d4wdib1 first appeared in SCOPe 2.05, called d4wdib_
  
• d4wdib1 appears in SCOPe 2.07
  
• d4wdib1 appears in the current release, SCOPe 2.08