SCOPe 2.08: Domain d4up2a_: 4up2 A:

Lineage for d4up2a_ (4up2 A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.67: PLP-dependent transferase-like [53382] (3 superfamilies)
   main domain: 3 layers: a/b/a, mixed beta-sheet of 7 strands, order 3245671; strand 7 is antiparallel to the rest

4. Superfamily c.67.1: PLP-dependent transferases [53383] (10 families)

5. Family c.67.1.2: Beta-eliminating lyases [53397] (3 proteins)

6. Protein Tryptophan indol-lyase (tryptophanase) [53400] (2 species)

7. Species Escherichia coli [TaxId:562] [159703] (7 PDB entries)
   Uniprot P0A853 5-471! Uniprot Q8XB34 5-471

8. Domain d4up2a_: 4up2 A: [274335]
   automated match to d2c44a1
   complexed with bme, so4

Details for d4up2a_

PDB Entry: 4up2, 2.78 Å

PDB Description: crystal structure of escherichia coli tryptophanase purified from alkaline stressed bacterial culture.

PDB Compounds: (A:) tryptophanase

SCOPe Domain Sequences for d4up2a_:

Sequence, based on SEQRES records:

>d4up2a_ c.67.1.2 (A:) Tryptophan indol-lyase (tryptophanase) {Escherichia coli [TaxId: 562]}
menfkhlpepfrirviepvkrttrayreeaiiksgmnpflldsedvfidlltdsgtgavt
qsmqaammrgdeaysgsrsyyalaesvknifgyqytipthqgrgaeqiyipvlikkreqe
kgldrskmvafsnyffdttqghsqingctvrnvyikeafdtgvrydfkgnfdleglergi
eevgpnnvpyivatitsnsaggqpvslanlkamysiakkydipvvmdsarfaenayfikq
reaeykdwtieqitretykyadmlamsakkdamvpmggllcmkddsffdvytecrtlcvv
qegfptyggleggamerlavglydgmnldwlayriaqvqylvdgleeigvvcqqagghaa
fvdagkllphipadqfpaqalacelykvagiraveigsfllgrdpktgkqlpcpaellrl
tipratytqthmdfiieafkhvkenasnikgltftyepkvlrhftakl

Sequence, based on observed residues (ATOM records):

>d4up2a_ c.67.1.2 (A:) Tryptophan indol-lyase (tryptophanase) {Escherichia coli [TaxId: 562]}
menfkhlpepfrirviepvkrttrayreeaiiksgmnpflldsedvfidlltdsgtgavt
qsmqaammrgdeaysgsrsyyalaesvknifgyqytipthqgrgaeqiyipvlikkreqe
kgldrskmvafsnyfctvrnvyikeafdtgvrydfkgnfdleglergieevgpnnvpyiv
atitsnsaggqpvslanlkamysiakkydipvvmdsarfaenayfikqreaeykdwtieq
itretykyadmlamsakkdamvpmggllcmkddsffgleggamerlavglydgmnldwla
yriaqvqylvdgleeigvvcqqagghaafvdagkllphipadqfpaqalacelykvagir
aveigpaellrltipratytqthmdfiieafkhvkenasnikgltftyepkvlrhftakl

Timeline for d4up2a_:

• d4up2a_ first appeared in SCOPe 2.05
  
• d4up2a_ appears in SCOPe 2.07