SCOPe 2.05: Domain d4zqna_: 4zqn A:

Lineage for d4zqna_ (4zqn A:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.5: Inosine monophosphate dehydrogenase (IMPDH) [51412] (2 families)
   The phosphate moiety of substrate binds in the 'common' phosphate-binding site

5. Family c.1.5.0: automated matches [227276] (1 protein)
   not a true family

6. Protein automated matches [227084] (8 species)
   not a true protein

7. Species Mycobacterium tuberculosis [TaxId:83332] [274113] (5 PDB entries)

8. Domain d4zqna_: 4zqn A: [274118]
   automated match to d4myxe_
   complexed with 4qo, imp

Details for d4zqna_

PDB Entry: 4zqn, 2 Å

PDB Description: crystal structure of the catalytic domain of the inosine monophosphate dehydrogenase from mycobacterium tuberculosis in the complex with imp and the inhibitor p41

PDB Compounds: (A:) Inosine-5'-monophosphate dehydrogenase,Inosine-5'-monophosphate dehydrogenase

SCOPe Domain Sequences for d4zqna_:

Sequence, based on SEQRES records:

>d4zqna_ c.1.5.0 (A:) automated matches {Mycobacterium tuberculosis [TaxId: 83332]}
dpvptggddphkvamlgltfddvlllpaasdvvpatadtssqltkkirlkvplvssamdt
vtesrmaiamaraggmgvlhrnlpvaeqagqvemvkrsggllvgaavgvggdawvramml
vdagvdvlvvdtahahnrlvldmvgklksevgdrvevvggnvatrsaaaalvdagadavk
vgvgpgsicttrvvagvgapqitaileavaacrpagvpviadgglqysgdiakalaagas
tamlgsllagtaeapgelifvngkqyksyrgmgslgamrgrggatsyskdryfaddalse
dklvpegiegrvpfrgplssvihqltgglraamgytgsptievlqqaqfvritpaglkes
hphdvamtveapny

Sequence, based on observed residues (ATOM records):

>d4zqna_ c.1.5.0 (A:) automated matches {Mycobacterium tuberculosis [TaxId: 83332]}
dpvptggddphkvamlgltfddvlllpaasdvvpatadtssqltkkirlkvplvssamdt
vtesrmaiamaraggmgvlhrnlpvaeqagqvemvkrsggllvgaavgvggdawvramml
vdagvdvlvvdtahahnrlvldmvgklksevgdrvevvggnvatrsaaaalvdagadavk
vgvgpgsicttrvvagvgapqitaileavaacrpagvpviadgglqysgdiakalaagas
tamlgsllagtaeapgelifvngkqyksyrgmgslgamrdklvpegiegrvpfrgplssv
ihqltgglraamgytgsptievlqqaqfvritpaglkeshphdvamtveapny

Timeline for d4zqna_:

• d4zqna_ is new in SCOPe 2.05-stable
  
• d4zqna_ appears in SCOPe 2.06
  
• d4zqna_ appears in the current release, SCOPe 2.08