SCOPe 2.08: Domain d4xy2b1: 4xy2 B:449-770

Lineage for d4xy2b1 (4xy2 B:449-770)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
   multihelical; consists of two different alpha-helical bundles

4. Superfamily a.211.1: HD-domain/PDEase-like [109604] (9 families)

5. Family a.211.1.0: automated matches [191566] (1 protein)
   not a true family

6. Protein automated matches [190983] (12 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188676] (139 PDB entries)

8. Domain d4xy2b1: 4xy2 B:449-770 [273944]
   Other proteins in same PDB: d4xy2a2, d4xy2b2
   automated match to d2ourb_
   complexed with 490, mg, zn

Details for d4xy2b1

PDB Entry: 4xy2, 2.03 Å

PDB Description: crystal structure of pde10a in complex with asp9436

PDB Compounds: (B:) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A

SCOPe Domain Sequences for d4xy2b1:

Sequence, based on SEQRES records:

>d4xy2b1 a.211.1.0 (B:449-770) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sictseewqglmqftlpvrlckeielfhfdigpfenmwpgifvymvhrscgtscfelekl
crfimsvkknyrrvpyhnwkhavtvahcmyailqnnhtlftdlerkglliaclchdldhr
gfsnsylqkfdhplaalyststmeqhhfsqtvsilqleghnifstlssseyeqvleiirk
aiiatdlalyfgnrkqleemyqtgslnlnnqshrdrviglmmtacdlcsvtklwpvtklt
andiyaefwaegdemkklgiqpipmmdrdkkdevpqgqlgfynavaipcyttltqilppt
epllkacrdnlsqwekvirgee

Sequence, based on observed residues (ATOM records):

>d4xy2b1 a.211.1.0 (B:449-770) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sictseewqglmqftlpvrlckeielfhfdigpfenmwpgifvymvhrscgtscfelekl
crfimsvkknyrrvpyhnwkhavtvahcmyailqnnhtlftdlerkglliaclchdldhr
gfsnsylqkfplaalyststmeqhhfsqtvsilqleghnifstlssseyeqvleiirkai
iatdlalyfgnrkqleemyqtgslnlnnqshrdrviglmmtacdlcsvtklwpvtkltan
diyaefwaegdemkklgiqpipmmdrdkkdevpqgqlgfynavaipcyttltqilpptep
llkacrdnlsqwekvirgee

Timeline for d4xy2b1:

• d4xy2b1 first appeared in SCOPe 2.05, called d4xy2b_
  
• d4xy2b1 appears in SCOPe 2.07