SCOPe 2.05: Domain d4xfta_: 4xft A:

Lineage for d4xfta_ (4xft A:)

1. Root: SCOPe 2.05

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.42: beta-Trefoil [50352] (8 superfamilies)
   barrel, closed; n=6, S=12; and a hairpin triplet; meander
   duplication: has internal pseudo threefold symmetry

4. Superfamily b.42.1: Cytokine [50353] (3 families)

5. Family b.42.1.2: Interleukin-1 (IL-1) [50362] (6 proteins)

6. Protein automated matches [190999] (1 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188735] (17 PDB entries)

8. Domain d4xfta_: 4xft A: [273799]
   automated match to d3wo2a_
   complexed with dms; mutant

Details for d4xfta_

PDB Entry: 4xft, 2 Å

PDB Description: structure of il-18 ser mutant iii

PDB Compounds: (A:) Interleukin-18

SCOPe Domain Sequences for d4xfta_:

Sequence, based on SEQRES records:

>d4xfta_ b.42.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
yfgklesklsvirnlndqvlfidqgnrplfedmtdsdcrdnaprtifiismykdsqprgm
avtisvacaaastlscenkiisfkemnppdnikdtksdiiffqrsvpghdnkmqfesssy
egyflacekerdlfklilkkedelgdrsimftvqn

Sequence, based on observed residues (ATOM records):

>d4xfta_ b.42.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
yfgklesklsvirnlndqvlfidqgnrplfedmtdsdcrdnaprtifiismykdsqprgm
avtisvacaaastlscenkiisfkemnppdnikdtksdiiffqrsvpghdnkmqfesssy
egyflacekerdlfklilkkeelgdrsimftvqn

Timeline for d4xfta_:

• d4xfta_ is new in SCOPe 2.05-stable
  
• d4xfta_ appears in SCOPe 2.06
  
• d4xfta_ appears in the current release, SCOPe 2.08