Lineage for d4rvla_ (4rvl A:)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2542179Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2542180Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2542316Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2542825Protein Cell cycle checkpoint kinase chk1 [64404] (1 species)
    CaMK group; CAMKL subfamily; serine/threonine kinase
  7. 2542826Species Human (Homo sapiens) [TaxId:9606] [64405] (85 PDB entries)
  8. 2542871Domain d4rvla_: 4rvl A: [273450]
    automated match to d2ydia_
    complexed with 3xl

Details for d4rvla_

PDB Entry: 4rvl (more details), 1.85 Å

PDB Description: chk1 kinase domain with diazacarbazole compound 7: 3-(2- hydroxyphenyl)-9h-pyrrolo[2,3-b:5,4-c']dipyridine-6-carbonitrile
PDB Compounds: (A:) Serine/threonine-protein kinase Chk1

SCOPe Domain Sequences for d4rvla_:

Sequence, based on SEQRES records: (download)

>d4rvla_ d.144.1.7 (A:) Cell cycle checkpoint kinase chk1 {Human (Homo sapiens) [TaxId: 9606]}
vpfvedwdlvqtlgegaygevqlavnrvteeavavkivdmkravdcpenikkeicinkml
nhenvvkfyghrregniqylfleycsggelfdriepdigmpepdaqrffhqlmagvvylh
gigithrdikpenlllderdnlkisdfglatvfrynnrerllnkmcgtlpyvapellkrr
efhaepvdvwscgivltamlagelpwdqpsdscqeysdwkekktylnpwkkidsaplall
hkilvenpsaritipdikkdrwynkplkkga

Sequence, based on observed residues (ATOM records): (download)

>d4rvla_ d.144.1.7 (A:) Cell cycle checkpoint kinase chk1 {Human (Homo sapiens) [TaxId: 9606]}
vpfvedwdlvqtlgvqlavnrvteeavavkivdmknikkeicinkmlnhenvvkfyghrr
egniqylfleycsggelfdriepdigmpepdaqrffhqlmagvvylhgigithrdikpen
lllderdnlkisdfglatvfrynnrerllnkmcgtlpyvapellkrrefhaepvdvwscg
ivltamlagelpwdqpsdscqeysdwkekktylnpwkkidsaplallhkilvenpsarit
ipdikkdrwynkplkkga

SCOPe Domain Coordinates for d4rvla_:

Click to download the PDB-style file with coordinates for d4rvla_.
(The format of our PDB-style files is described here.)

Timeline for d4rvla_: