Lineage for d4y8za_ (4y8z A:)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2055629Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. 2055630Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families) (S)
  5. 2058159Family b.47.1.0: automated matches [191364] (1 protein)
    not a true family
  6. 2058160Protein automated matches [190438] (24 species)
    not a true protein
  7. 2058190Species Human (Homo sapiens) [TaxId:9606] [187421] (54 PDB entries)
  8. 2058228Domain d4y8za_: 4y8z A: [273269]
    automated match to d1p57b_
    complexed with 4ce, edo, so4

Details for d4y8za_

PDB Entry: 4y8z (more details), 2.2 Å

PDB Description: factor xia in complex with the inhibitor (2e)-n-[(1s)-1-[5-chloro-4- (4-hydroxy-2-oxo-1,2-dihydroquinolin-6-yl)-1h-imidazol-2-yl]-3-(4- methylpiperazin-1-yl)-3-oxopropyl]-3-[5-chloro-2-(1h-tetrazol-1-yl) phenyl]prop-2-enamide
PDB Compounds: (A:) coagulation factor xia

SCOPe Domain Sequences for d4y8za_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4y8za_ b.47.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d4y8za_:

Click to download the PDB-style file with coordinates for d4y8za_.
(The format of our PDB-style files is described here.)

Timeline for d4y8za_: