SCOPe 2.07: Domain d3wv1b_: 3wv1 B:

Lineage for d3wv1b_ (3wv1 B:)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.92: Zincin-like [55485] (2 superfamilies)
   contains mixed beta sheet with connection over free side of the sheet

4. Superfamily d.92.1: Metalloproteases ("zincins"), catalytic domain [55486] (18 families)

5. Family d.92.1.11: Matrix metalloproteases, catalytic domain [55528] (14 proteins)

6. Protein Collagenase-3 (MMP-13) [55540] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [55541] (46 PDB entries)

8. Domain d3wv1b_: 3wv1 B: [273012]
   automated match to d1euba_
   complexed with ca, fmt, na, whh, zn

Details for d3wv1b_

PDB Entry: 3wv1, 1.98 Å

PDB Description: crystal structure of the catalytic domain of mmp-13 complexed with 4- (2-((6-fluoro-2-((3-methoxybenzyl)carbamoyl)-4-oxo-3,4- dihydroquinazolin-5-yl)oxy)ethyl)benzoic acid

PDB Compounds: (B:) collagenase 3

SCOPe Domain Sequences for d3wv1b_:

Sequence, based on SEQRES records:

>d3wv1b_ d.92.1.11 (B:) Collagenase-3 (MMP-13) {Human (Homo sapiens) [TaxId: 9606]}
ynvfprtlkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiadi
misfgikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaahe
fghslgldhskdpgalmfpiytytgkshfmlpdddvqgiqslygpg

Sequence, based on observed residues (ATOM records):

>d3wv1b_ d.92.1.11 (B:) Collagenase-3 (MMP-13) {Human (Homo sapiens) [TaxId: 9606]}
ynvftlkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiadimi
sfgikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaahefg
hslgldhskdpgalmfpiytytgkshfmlpdddvqgiqslygpg

Timeline for d3wv1b_:

• d3wv1b_ first appeared in SCOPe 2.05
  
• d3wv1b_ appears in SCOPe 2.06
  
• d3wv1b_ appears in the current release, SCOPe 2.08