SCOPe 2.06: Domain d4zk4c1: 4zk4 C:1-206

Lineage for d4zk4c1 (4zk4 C:1-206)

1. Root: SCOPe 2.06

2. Class b: All beta proteins [48724] (177 folds)

3. Fold b.96: Nicotinic receptor ligand binding domain-like [63711] (1 superfamily)
   sandwich; 8 strands in 2 sheets; greek-key: partial topological similarity to immunoglobulin-like folds

4. Superfamily b.96.1: Nicotinic receptor ligand binding domain-like [63712] (2 families)

5. Family b.96.1.0: automated matches [193505] (1 protein)
   not a true family

6. Protein automated matches [193506] (6 species)
   not a true protein

7. Species California sea hare (Aplysia californica) [TaxId:6500] [230583] (48 PDB entries)

8. Domain d4zk4c1: 4zk4 C:1-206 [272832]
   Other proteins in same PDB: d4zk4a2, d4zk4b2, d4zk4c2, d4zk4d2, d4zk4e2
   automated match to d3sioc_
   complexed with mg, pg4, so4, tii

Details for d4zk4c1

PDB Entry: 4zk4, 1.9 Å

PDB Description: crystal structure of a chimeric acetylcholine binding protein from aplysia californica (ac-achbp) containing loop c from the human alpha 3 nicotinic acetylcholine receptor in complex with 7-(5-isopropoxy- pyridin-3-yl)-1-methyl-1,7-diaza-spiro[4.4]nonane

PDB Compounds: (C:) soluble acetylcholine receptor, neuronal acetylcholine receptor subunit alpha-3 chimera

SCOPe Domain Sequences for d4zk4c1:

Sequence, based on SEQRES records:

>d4zk4c1 b.96.1.0 (C:1-206) automated matches {California sea hare (Aplysia californica) [TaxId: 6500]}
hsqanlmrlksdlfnrspmypgptkddpltvtlgftlqdivkadsstnevdlvyweqqrw
klnslmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipa
qrlsfmcdptgvdseegatcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsat
qykhdikyncceeiypdvvlvvkfre

Sequence, based on observed residues (ATOM records):

>d4zk4c1 b.96.1.0 (C:1-206) automated matches {California sea hare (Aplysia californica) [TaxId: 6500]}
hsqanlmrlksdlfnypgptkddpltvtlgftlqdivkadsstnevdlvyweqqrwklns
lmwdpneygnitdfrtsaadiwtpditaysstrpvqvlspqiavvthdgsvmfipaqrls
fmcdptgvdseegatcavkfgswvysgfeidlktdtdqvdlssyyasskyeilsatqykh
dikyncceeiypdvvlvvkfre

Timeline for d4zk4c1:

• d4zk4c1 first appeared in SCOPe 2.05, called d4zk4c_
  
• d4zk4c1 appears in SCOPe 2.07
  
• d4zk4c1 appears in the current release, SCOPe 2.08