SCOPe 2.08: Domain d4yhfa_: 4yhf A:

Lineage for d4yhfa_ (4yhf A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (20 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (850 PDB entries)

8. Domain d4yhfa_: 4yhf A: [272790]
   automated match to d3pj2a_
   complexed with 4c9, cl, edo, na, so4

Details for d4yhfa_

PDB Entry: 4yhf, 2.2 Å

PDB Description: bruton's tyrosine kinase in complex with a t-butyl cyanoacrylamide inhibitor

PDB Compounds: (A:) Tyrosine-protein kinase BTK

SCOPe Domain Sequences for d4yhfa_:

Sequence; same for both SEQRES and ATOM records:

>d4yhfa_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
gygsweidpkdltflkelgtgqfgvvkygkwrgqydvaikmikegsmsedefieeakvmm
nlsheklvqlygvctkqrpifiiteymangcllnylremrhrfqtqqllemckdvceame
yleskqflhrdlaarnclvndqgvvkvsdfglsryvlddeytssvgskfpvrwsppevlm
yskfssksdiwafgvlmweiyslgkmpyerftnsetaehiaqglrlyrphlasekvytim
yscwhekaderptfkillsnildvmdee

Timeline for d4yhfa_:

• d4yhfa_ first appeared in SCOPe 2.05
  
• d4yhfa_ appears in SCOPe 2.07