SCOPe 2.05: Domain d4y2ya1: 4y2y A:2-227

Lineage for d4y2ya1 (4y2y A:2-227)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.108: HAD-like [56783] (1 superfamily)
   3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456

4. Superfamily c.108.1: HAD-like [56784] (26 families)
   usually contains an insertion (sub)domain after strand 1

5. Family c.108.1.2: YihX-like [56789] (3 proteins)
   the insertion subdomain is a 4-helical bundle
   automatically mapped to Pfam PF13419

6. Protein Epoxide hydrolase, N-terminal domain [56790] (2 species)
   has a lipid phosphatase activity

7. Species Human (Homo sapiens) [TaxId:9606] [102303] (35 PDB entries)

8. Domain d4y2ya1: 4y2y A:2-227 [272449]
   Other proteins in same PDB: d4y2ya2
   automated match to d1zd3a1
   complexed with 49z, mg

Details for d4y2ya1

PDB Entry: 4y2y, 2.3 Å

PDB Description: structure of soluble epoxide hydrolase in complex with 2-(2- fluorophenyl)-n-[(5-methyl-2-thienyl)methyl]ethanamine

PDB Compounds: (A:) Bifunctional epoxide hydrolase 2

SCOPe Domain Sequences for d4y2ya1:

Sequence; same for both SEQRES and ATOM records:

>d4y2ya1 c.108.1.2 (A:2-227) Epoxide hydrolase, N-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
tlraavfdldgvlalpavfgvlgrteealalprgllndafqkggpegattrlmkgeitls
qwiplmeencrkcsetakvclpknfsikeifdkaisarkinrpmlqaalmlrkkgfttai
ltntwlddraerdglaqlmcelkmhfdfliescqvgmvkpepqiykflldtlkaspsevv
flddiganlkpardlgmvtilvqdtdtalkelekvtgiqllntpap

Timeline for d4y2ya1:

• d4y2ya1 is new in SCOPe 2.05-stable
  
• d4y2ya1 appears in SCOPe 2.06
  
• d4y2ya1 appears in the current release, SCOPe 2.08