SCOPe 2.07: Domain d4zbia1: 4zbi A:172-322

Lineage for d4zbia1 (4zbi A:172-322)

1. Root: SCOPe 2.07

2. Class f: Membrane and cell surface proteins and peptides [56835] (60 folds)

3. Fold f.1: Toxins' membrane translocation domains [56836] (5 superfamilies)
   multi-helical domains of various folds which is thought to unfold in the membrane

4. Superfamily f.1.4: Bcl-2 inhibitors of programmed cell death [56854] (2 families)
   PROVISIONAL CLASSIFICATION, based on structural similarity to the diphtheria toxin domain

5. Family f.1.4.1: Bcl-2 inhibitors of programmed cell death [56855] (11 proteins)
   Pfam PF00452

6. Protein automated matches [190236] (3 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188722] (88 PDB entries)

8. Domain d4zbia1: 4zbi A:172-322 [272092]
   Other proteins in same PDB: d4zbia2, d4zbib2, d4zbic2, d4zbid2, d4zbie2, d4zbif2, d4zbig2, d4zbih2, d4zbii2, d4zbij2, d4zbik2, d4zbil2
   automated match to d2mhsa_
   complexed with 4m6

Details for d4zbia1

PDB Entry: 4zbi, 2.5 Å

PDB Description: mcl-1 complexed with small molecules

PDB Compounds: (A:) Induced myeloid leukemia cell differentiation protein Mcl-1

SCOPe Domain Sequences for d4zbia1:

Sequence; same for both SEQRES and ATOM records:

>d4zbia1 f.1.4.1 (A:172-322) automated matches {Human (Homo sapiens) [TaxId: 9606]}
delyrqsleiisrylreqatgakdtkpmgrsgatsrkaletlrrvgdgvqrnhetafqgm
lrkldikneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakhlktinqesciepla
esitdvlvrtkrdwlvkqrgwdgfveffhve

Timeline for d4zbia1:

• d4zbia1 first appeared in SCOPe 2.05, called d4zbia_
  
• d4zbia1 appears in SCOPe 2.06
  
• d4zbia1 appears in the current release, SCOPe 2.08