SCOPe 2.06: Domain d4uiya1: 4uiy A:44-168

Lineage for d4uiya1 (4uiy A:44-168)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.29: Bromodomain-like [47363] (15 superfamilies)
   4 helices; bundle; minor mirror variant of up-and-down topology

4. Superfamily a.29.2: Bromodomain [47370] (2 families)

5. Family a.29.2.0: automated matches [191428] (1 protein)
   not a true family

6. Protein automated matches [190615] (10 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187641] (647 PDB entries)

8. Domain d4uiya1: 4uiy A:44-168 [271715]
   Other proteins in same PDB: d4uiya2
   automated match to d3u5la_
   complexed with 5v2, edo

Details for d4uiya1

PDB Entry: 4uiy, 1.3 Å

PDB Description: n-terminal bromodomain of human brd4 with n-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4h,5h-thieno-3,2-c- pyridine-2-carboximidamide

PDB Compounds: (A:) Bromodomain-containing protein 4

SCOPe Domain Sequences for d4uiya1:

Sequence; same for both SEQRES and ATOM records:

>d4uiya1 a.29.2.0 (A:44-168) automated matches {Human (Homo sapiens) [TaxId: 9606]}
nppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykiikt
pmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqkine
lptee

Timeline for d4uiya1:

• d4uiya1 first appeared in SCOPe 2.05, called d4uiya_
  
• d4uiya1 appears in SCOPe 2.07
  
• d4uiya1 appears in the current release, SCOPe 2.08