SCOPe 2.07: Domain d4uiza1: 4uiz A:44-168

Lineage for d4uiza1 (4uiz A:44-168)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.29: Bromodomain-like [47363] (15 superfamilies)
   4 helices; bundle; minor mirror variant of up-and-down topology

4. Superfamily a.29.2: Bromodomain [47370] (2 families)

5. Family a.29.2.0: automated matches [191428] (1 protein)
   not a true family

6. Protein automated matches [190615] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187641] (1004 PDB entries)

8. Domain d4uiza1: 4uiz A:44-168 [271711]
   Other proteins in same PDB: d4uiza2
   automated match to d3u5la_
   complexed with edo, n1d

Details for d4uiza1

PDB Entry: 4uiz, 1.19 Å

PDB Description: n-terminal bromodomain of human brd4 with 7-(3,4- dimethoxyphenyl)-2-(4-methanesulfonylpiperazine-1-carbonyl) -5-methyl-4h,5h-thieno-3,2-c-pyridin-4-one

PDB Compounds: (A:) Bromodomain-containing protein 4

SCOPe Domain Sequences for d4uiza1:

Sequence; same for both SEQRES and ATOM records:

>d4uiza1 a.29.2.0 (A:44-168) automated matches {Human (Homo sapiens) [TaxId: 9606]}
nppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykiikt
pmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqkine
lptee

Timeline for d4uiza1:

• d4uiza1 first appeared in SCOPe 2.05, called d4uiza_
  
• d4uiza1 appears in SCOPe 2.06
  
• d4uiza1 appears in the current release, SCOPe 2.08