SCOPe 2.05: Domain d5ak2b_: 5ak2 B:

Lineage for d5ak2b_ (5ak2 B:)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.0: automated matches [191623] (1 protein)
   not a true family

6. Protein automated matches [191142] (5 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [189274] (19 PDB entries)

8. Domain d5ak2b_: 5ak2 B: [271608]
   automated match to d2pjla_
   complexed with 85z

Details for d5ak2b_

PDB Entry: 5ak2, 2.19 Å

PDB Description: oxyphenylpropenoic acids as oral selective estrogen receptor down- regulators.

PDB Compounds: (B:) Estrogen receptor

SCOPe Domain Sequences for d5ak2b_:

Sequence, based on SEQRES records:

>d5ak2b_ a.123.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrvpgf
vdltlhdqvhllesawleilmiglvwrsmehpgkllfapnllldrnqgksvegmveifdm
llatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdtli
hlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmksknvvpsydlllemld

Sequence, based on observed residues (ATOM records):

>d5ak2b_ a.123.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lsltadqmvsalldaeppilysepfseasmmglltnladrelvhminwakrvpgfvdltl
hdqvhllesawleilmiglvwrsmehpgkllfapnllldrnqgksvegmveifdmllats
srfrmmnlqgeefvclksiillnsgvykdhihrvldkitdtlihlmakagltlqqqhqrl
aqlllilshirhmsnkgmehlysmllemld

Timeline for d5ak2b_:

• d5ak2b_ is new in SCOPe 2.05-stable
  
• d5ak2b_ appears in SCOPe 2.06
  
• d5ak2b_ appears in the current release, SCOPe 2.08