Lineage for d4xueb1 (4xue B:52-265)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2129295Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
    core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest
  4. 2129296Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (60 families) (S)
  5. 2129297Family c.66.1.1: COMT-like [53336] (4 protein domains)
  6. 2129308Protein Catechol O-methyltransferase, COMT [53337] (2 species)
  7. 2129309Species Human (Homo sapiens) [TaxId:9606] [267759] (10 PDB entries)
  8. 2129317Domain d4xueb1: 4xue B:52-265 [271577]
    Other proteins in same PDB: d4xueb2
    automated match to d3bwma_
    complexed with 43j, mg, sam

Details for d4xueb1

PDB Entry: 4xue (more details), 2.3 Å

PDB Description: synthesis and evaluation of heterocyclic catechol mimics as inhibitors of catechol-o-methyltransferase (comt): structure with cmpd27b
PDB Compounds: (B:) Catechol O-methyltransferase

SCOPe Domain Sequences for d4xueb1:

Sequence; same for both SEQRES and ATOM records: (download)

>d4xueb1 c.66.1.1 (B:52-265) Catechol O-methyltransferase, COMT {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d4xueb1:

Click to download the PDB-style file with coordinates for d4xueb1.
(The format of our PDB-style files is described here.)

Timeline for d4xueb1:

  • d4xueb1 first appeared in SCOPe 2.05, called d4xueb_

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