Lineage for d4wdxa_ (4wdx A:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2078560Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2080913Superfamily c.1.7: NAD(P)-linked oxidoreductase [51430] (2 families) (S)
  5. 2080914Family c.1.7.1: Aldo-keto reductases (NADP) [51431] (16 protein domains)
    Common fold covers whole protein structure
  6. 2081137Protein Prostaglandin d2 11-ketoreductase (akr1c3) [102051] (1 species)
    Aldo-keto reductase family 1 member c3
  7. 2081138Species Human (Homo sapiens) [TaxId:9606] [102052] (43 PDB entries)
    Uniprot P42330
  8. 2081167Domain d4wdxa_: 4wdx A: [271538]
    automated match to d1s1pa_
    complexed with nap, wdx

Details for d4wdxa_

PDB Entry: 4wdx (more details), 1.64 Å

PDB Description: 17beta-hsd5 in complex with [4-(2-hydroxyethyl)piperidin-1-yl](5- methyl-1h-indol-2-yl)methanone
PDB Compounds: (A:) Aldo-keto reductase family 1 member C3

SCOPe Domain Sequences for d4wdxa_:

Sequence, based on SEQRES records: (download)

>d4wdxa_ c.1.7.1 (A:) Prostaglandin d2 11-ketoreductase (akr1c3) {Human (Homo sapiens) [TaxId: 9606]}
qcvklndghfmpvlgfgtyappevprskalevtklaieagfrhidsahlynneeqvglai
rskiadgsvkredifytsklwstfhrpelvrpalenslkkaqldyvdlylihspmslkpg
eelsptdengkvifdivdlcttweamekckdaglaksigvsnfnrrqlemilnkpglkyk
pvcnqvechpyfnrsklldfckskdivlvaysalgsqrdkrwvdpnspvlledpvlcala
kkhkrtpalialryqlqrgvvvlaksyneqrirqnvqvfefqltaedmkaidgldrnlhy
fnsdsf

Sequence, based on observed residues (ATOM records): (download)

>d4wdxa_ c.1.7.1 (A:) Prostaglandin d2 11-ketoreductase (akr1c3) {Human (Homo sapiens) [TaxId: 9606]}
qcvklndghfmpvlgfgtyappevprskalevtklaieagfrhidsahlynneeqvglai
rskiadgsvkredifytsklwstfhrpelvrpalenslkkaqldyvdlylihspmslkpg
lsptifdivdlcttweamekckdaglaksigvsnfnrrqlemilnkpglkykpvcnqvec
hpyfnrsklldfckskdivlvaysalgsqrdkrwvdpnspvlledpvlcalakkhkrtpa
lialryqlqrgvvvlaksyneqrirqnvqvfefqltaedmkaidgldrnlhyfnsdsf

SCOPe Domain Coordinates for d4wdxa_:

Click to download the PDB-style file with coordinates for d4wdxa_.
(The format of our PDB-style files is described here.)

Timeline for d4wdxa_: