SCOPe 2.08: Domain d4rxaa_: 4rxa A:

Lineage for d4rxaa_ (4rxa A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.128: Terpenoid synthases [48575] (1 superfamily)
   multihelical; core: 8 helices (C-J) are arranged in 2 parallel layers

4. Superfamily a.128.1: Terpenoid synthases [48576] (6 families)
   duplication: two metal-binding sites are related by a pseudo dyad that also relates helices C-F to helices G-J

5. Family a.128.1.1: Isoprenyl diphosphate synthases [48577] (4 proteins)

6. Protein automated matches [190489] (5 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187688] (85 PDB entries)

8. Domain d4rxaa_: 4rxa A: [271508]
   automated match to d4demf_
   complexed with 3f2, po4

Details for d4rxaa_

PDB Entry: 4rxa, 2.2 Å

PDB Description: crystal structure of human farnesyl diphosphate synthase in complex with bph-1358

PDB Compounds: (A:) farnesyl pyrophosphate synthase

SCOPe Domain Sequences for d4rxaa_:

Sequence, based on SEQRES records:

>d4rxaa_ a.128.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
qekqdfvqhfsqivrvltedemghpeigdaiarlkevleynaiggkynrgltvvvafrel
veprkqdadslqrawtvgwcvellqafflvaddimdssltrrgqicwyqkpgvgldaind
anlleaciyrllklycreqpyylnlielflqssyqteigqtldlltapqgnvdlvrftek
ryksivkyktafysfylpiaaamymagidgekehanakkillemgeffqiqddyldlfgd
psvtgkigtdiqdnkcswlvvqclqratpeqyqilkenygqkeaekvarvkalyeeldlp
avflqyeedsyshimalieqyaaplppavflglarkiyk

Sequence, based on observed residues (ATOM records):

>d4rxaa_ a.128.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
qekqdfvqhfsqivrvltedemghpeigdaiarlkevleynaiggkynrgltvvvafrel
vprkqdadslqrawtvgwcvellqafflvaddimdssltrrgqicwyqkpgvgldainda
nlleaciyrllklycreqpyylnlielflqssyqteigqtldlltapqnvdlvrftekry
ksivkyktafysfylpiaaamymagidgekehanakkillemgeffqiqddyldlfgdps
vtgkigtdiqdnkcswlvvqclqratpeqyqikenygqvavkalyeeldlpavflqyeed
syshimalieqyaaplppavflglarkiyk

Timeline for d4rxaa_:

• d4rxaa_ first appeared in SCOPe 2.05
  
• d4rxaa_ appears in SCOPe 2.07