Lineage for d4q50d_ (4q50 D:)

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2341330Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
    multihelical; 3 layers or orthogonally packed helices
  4. 2341331Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families) (S)
  5. 2341332Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)
  6. 2341442Protein Estrogen receptor alpha [48519] (1 species)
  7. 2341443Species Human (Homo sapiens) [TaxId:9606] [48520] (82 PDB entries)
    Uniprot P03372 307-551
  8. 2341629Domain d4q50d_: 4q50 D: [271428]
    automated match to d3q95b_
    complexed with oht, so4; mutant

Details for d4q50d_

PDB Entry: 4q50 (more details), 3.07 Å

PDB Description: the estrogen receptor alpha ligand binding domain d538g mutant in complex with 4-hydroxytamoxifen
PDB Compounds: (D:) Estrogen receptor

SCOPe Domain Sequences for d4q50d_:

Sequence, based on SEQRES records: (download)

>d4q50d_ a.123.1.1 (D:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
lalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrvp
gfvdltlhdqvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmveif
dmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitdt
lihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplyglllemld

Sequence, based on observed residues (ATOM records): (download)

>d4q50d_ a.123.1.1 (D:) Estrogen receptor alpha {Human (Homo sapiens) [TaxId: 9606]}
lalsltadqmvsalldaeppilyseasmmglltnladrelvhminwakrvpgfvdltlhd
qvhllecawleilmiglvwrsmehpgkllfapnllldrnqgkcvegmveifdmllatssr
frmmnlqgeefvclksiillnsgvksleekdhihrvldkitdtlihlmakagltlqqqhq
rlaqlllilshirhmsnkgmehlysmlyglllemld

SCOPe Domain Coordinates for d4q50d_:

Click to download the PDB-style file with coordinates for d4q50d_.
(The format of our PDB-style files is described here.)

Timeline for d4q50d_: