Lineage for d4pvga_ (4pvg A:)

  1. Root: SCOPe 2.05
  2. 1815291Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 1851756Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423
  4. 1851757Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (6 families) (S)
    share with the family I the common active site structure with a circularly permuted topology
  5. 1851855Family c.45.1.2: Higher-molecular-weight phosphotyrosine protein phosphatases [52805] (7 proteins)
    has an extension to the beta-sheet of 3 antiparallel strands before strand 4
  6. 1852048Protein automated matches [190252] (3 species)
    not a true protein
  7. 1852049Species Human (Homo sapiens) [TaxId:9606] [187034] (22 PDB entries)
  8. 1852078Domain d4pvga_: 4pvg A: [271412]
    automated match to d4hjpa_
    complexed with 2wt

Details for d4pvga_

PDB Entry: 4pvg (more details), 2.4 Å

PDB Description: crystal structure of protein tyrosine phosphatase shp2 catalytic domain complex with small molecular compound l88n79
PDB Compounds: (A:) Tyrosine-protein phosphatase non-receptor type 11

SCOPe Domain Sequences for d4pvga_:

Sequence, based on SEQRES records: (download)

>d4pvga_ c.45.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
fetlqqqeckllysrkegqrqenknknryknilpfdhtrvvlhdgdpnepvsdyinanii
mpefetkcnnskpkksyiatqgclqntvndfwrmvfqensrvivmttkevergkskcvky
wpdeyalkeygvmrvrnvkesaahdytlrelklskvgqgntertvwqyhfrtwpdhgvps
dpggvldfleevhhkqesimdagpvvvhcsagigrtgtfividilidiirekgvdcdidv
pktiqmvrsqrsgmvqteaqyrfiymavqhyietl

Sequence, based on observed residues (ATOM records): (download)

>d4pvga_ c.45.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
fetlqqqeckllysrkegqrqenknknryknilpfdhtrvvlhdgdpnepvsdyinanii
mpeksyiatqgclqntvndfwrmvfqensrvivmttkevergkskcvkywpdeyalkeyg
vmrvrnvkesaahdytlrelklskvgqgntertvwqyhfrtwpdhgvpsdpggvldflee
vhhkqesimdagpvvvhcsagigrtgtfividilidiirekgvdcdidvpktiqmvrsqr
sgmvqteaqyrfiymavqhyietl

SCOPe Domain Coordinates for d4pvga_:

Click to download the PDB-style file with coordinates for d4pvga_.
(The format of our PDB-style files is described here.)

Timeline for d4pvga_: