SCOPe 2.08: Domain d4x6xa_: 4x6x A:

Lineage for d4x6xa_ (4x6x A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest

4. Superfamily c.69.1: alpha/beta-Hydrolases [53474] (43 families)
   many members have left-handed crossover connection between strand 8 and additional strand 9

5. Family c.69.1.11: Epoxide hydrolase [53525] (3 proteins)

6. Protein Mammalian epoxide hydrolase, C-terminal domain [53526] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [102626] (49 PDB entries)

8. Domain d4x6xa_: 4x6x A: [271333]
   automated match to d1s8oa2
   complexed with s74

Details for d4x6xa_

PDB Entry: 4x6x, 1.8 Å

PDB Description: human soluble epoxide hydrolase in complex with a three substituted cyclopropane derivative

PDB Compounds: (A:) Bifunctional epoxide hydrolase 2

SCOPe Domain Sequences for d4x6xa_:

Sequence; same for both SEQRES and ATOM records:

>d4x6xa_ c.69.1.11 (A:) Mammalian epoxide hydrolase, C-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
tscnpsdmshgyvtvkprvrlhfvelgsgpavclchgfpeswyswryqipalaqagyrvl
amdmkgygessappeieeycmevlckemvtfldklglsqavfighdwggmlvwymalfyp
ervravaslntpfipanpnmsplesikanpvfdyqlyfqepgvaeaeleqnlsrtfkslf
rasdesvlsmhkvceagglfvnspeepslsrmvteeeiqfyvqqfkksgfrgplnwyrnm
ernwkwackslgrkilipalmvtaekdfvlvpqmsqhmedwiphlkrghiedcghwtqmd
kptevnqilikwldsd

Timeline for d4x6xa_:

• d4x6xa_ first appeared in SCOPe 2.05
  
• d4x6xa_ appears in SCOPe 2.07