Lineage for d4rn2a_ (4rn2 A:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2115321Fold c.42: Arginase/deacetylase [52767] (1 superfamily)
    3 layers: a/b/a, parallel beta-sheet of 8 strands, order 21387456
  4. 2115322Superfamily c.42.1: Arginase/deacetylase [52768] (3 families) (S)
  5. 2115600Family c.42.1.2: Histone deacetylase, HDAC [52773] (4 protein domains)
    automatically mapped to Pfam PF00850
  6. 2115643Protein automated matches [190786] (1 species)
    not a true protein
  7. 2115644Species Human (Homo sapiens) [TaxId:9606] [188039] (33 PDB entries)
  8. 2115682Domain d4rn2a_: 4rn2 A: [271224]
    automated match to d4qa0a_
    complexed with k, l7g, zn

Details for d4rn2a_

PDB Entry: 4rn2 (more details), 2.39 Å

PDB Description: crystal structure of s39d hdac8 in complex with a largazole analogue.
PDB Compounds: (A:) Histone deacetylase 8

SCOPe Domain Sequences for d4rn2a_:

Sequence, based on SEQRES records: (download)

>d4rn2a_ c.42.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
vpvyiyspeyvsmcdslakipkradmvhslieayalhkqmrivkpkvasmeematfhtda
ylqhlqkvsqegdddhpdsieyglgydcpategifdyaaaiggatitaaqclidgmckva
inwsggwhhakkdeasgfcylndavlgilrlrrkferilyvdldlhhgdgvedafsftsk
vmtvslhkfspgffpgtgdvsdvglgkgryysvnvpiqdgiqdekyyqicesvlkevyqa
fnpkavvlqlgadtiagdpmcsfnmtpvgigkclkyilqwqlatlilggggynlantarc
wtyltgvilgktlsseipdhefftaygpdyvleitpscrpdrnephriqqilnyikgnlk
hvv

Sequence, based on observed residues (ATOM records): (download)

>d4rn2a_ c.42.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
vpvyiyspeyvsmcdslakipkradmvhslieayalhkqmrivkpkvasmeematfhtda
ylqhlqkvsqsieygltegifdyaaaiggatitaaqclidgmckvainwsggwhhakkde
asgfcylndavlgilrlrrkferilyvdldlhhgdgvedafsftskvmtvslhkfspgff
pgtgdvsdvglgkgryysvnvpiqdgiqdekyyqicesvlkevyqafnpkavvlqlgadt
iagdpmcsfnmtpvgigkclkyilqwqlatlilggggynlantarcwtyltgvilgktls
seipdhefftaygpdyvleitpscrpdrnephriqqilnyikgnlkhvv

SCOPe Domain Coordinates for d4rn2a_:

Click to download the PDB-style file with coordinates for d4rn2a_.
(The format of our PDB-style files is described here.)

Timeline for d4rn2a_: