SCOPe 2.08: Domain d4pqea_: 4pqe A:

Lineage for d4pqea_ (4pqe A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.69: alpha/beta-Hydrolases [53473] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 8 strands, order 12435678, strand 2 is antiparallel to the rest

4. Superfamily c.69.1: alpha/beta-Hydrolases [53474] (43 families)
   many members have left-handed crossover connection between strand 8 and additional strand 9

5. Family c.69.1.1: Acetylcholinesterase-like [53475] (6 proteins)
   automatically mapped to Pfam PF00135

6. Protein Acetylcholinesterase [53476] (6 species)

7. Species Human (Homo sapiens) [TaxId:9606] [53480] (52 PDB entries)

8. Domain d4pqea_: 4pqe A: [271186]
   automated match to d2xupa_

Details for d4pqea_

PDB Entry: 4pqe, 2.9 Å

PDB Description: crystal structure of human acetylcholinesterase

PDB Compounds: (A:) acetylcholinesterase

SCOPe Domain Sequences for d4pqea_:

Sequence, based on SEQRES records:

>d4pqea_ c.69.1.1 (A:) Acetylcholinesterase {Human (Homo sapiens) [TaxId: 9606]}
daellvtvrggrlrgirlktpggpvsaflgipfaeppmgprrflppepkqpwsgvvdatt
fqsvcyqyvdtlypgfegtemwnpnrelsedclylnvwtpyprptsptpvlvwiygggfy
sgassldvydgrflvqaertvlvsmnyrvgafgflalpgsreapgnvglldqrlalqwvq
envaafggdptsvtlfgesagaasvgmhllsppsrglfhravlqsgapngpwatvgmgea
rrratqlahlvgcppggtggndtelvaclrtrpaqvlvnhewhvlpqesvfrfsfvpvvd
gdflsdtpealinagdfhglqvlvgvvkdegsyflvygapgfskdneslisraeflagvr
vgvpqvsdlaaeavvlhytdwlhpedparlrealsdvvgdhnvvcpvaqlagrlaaqgar
vyayvfehrastlswplwmgvphgyeiefifgipldpsrnytaeekifaqrlmrywanfa
rtgdpneprdpkapqwppytagaqqyvsldlrplevrrglraqacafwnrflpklls

Sequence, based on observed residues (ATOM records):

>d4pqea_ c.69.1.1 (A:) Acetylcholinesterase {Human (Homo sapiens) [TaxId: 9606]}
daellvtvrggrlrgirlktpggpvsaflgipfaeppmgprrflppepkqpwsgvvdatt
fqsvcyqyvdtlypgfegtemwnpnrelsedclylnvwtpyprptsptpvlvwiygggfy
sgassldvydgrflvqaertvlvsmnyrvgafgflalpgsreapgnvglldqrlalqwvq
envaafggdptsvtlfgesagaasvgmhllsppsrglfhravlqsgapngpwatvgmgea
rrratqlahlvgcpndtelvaclrtrpaqvlvnhewhvlsvfrfsfvpvvdgdflsdtpe
alinagdfhglqvlvgvvkdegsyflvygapgfskdneslisraeflagvrvgvpqvsdl
aaeavvlhytdwlhpedparlrealsdvvgdhnvvcpvaqlagrlaaqgarvyayvfehr
astlswplwmgvphgyeiefifgipldpsrnytaeekifaqrlmrywanfartgdpnepr
dpkapqwppytagaqqyvsldlrplevrrglraqacafwnrflpklls

Timeline for d4pqea_:

• d4pqea_ first appeared in SCOPe 2.05
  
• d4pqea_ appears in SCOPe 2.07