Lineage for d4x6pa_ (4x6p A:)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2055629Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. 2055630Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families) (S)
  5. 2055877Family b.47.1.2: Eukaryotic proteases [50514] (49 protein domains)
  6. 2056220Protein Coagulation factor XI [117237] (1 species)
  7. 2056221Species Human (Homo sapiens) [TaxId:9606] [117238] (44 PDB entries)
    Uniprot P03951 388-624
  8. 2056249Domain d4x6pa_: 4x6p A: [270825]
    automated match to d3bg8a_
    complexed with 3yu, cit, gol, nag

Details for d4x6pa_

PDB Entry: 4x6p (more details), 1.93 Å

PDB Description: factor xia (pichia pastoris; c500s [c122s]) in complex with the inhibitor (2e)-n-{(1s)-1-[4-(3-amino-1h-indazol-6-yl)-1h-imidazol-2- yl]-2-phenylethyl}-3-[5-chloro-2-(1h-tetrazol-1-yl)phenyl]prop-2- enamide
PDB Compounds: (A:) coagulation factor xi, light chain

SCOPe Domain Sequences for d4x6pa_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4x6pa_ b.47.1.2 (A:) Coagulation factor XI {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d4x6pa_:

Click to download the PDB-style file with coordinates for d4x6pa_.
(The format of our PDB-style files is described here.)

Timeline for d4x6pa_: