Lineage for d4mpwb_ (4mpw B:)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2055629Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. 2055630Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families) (S)
  5. 2055877Family b.47.1.2: Eukaryotic proteases [50514] (49 protein domains)
  6. 2055993Protein beta-Tryptase [50546] (1 species)
    ring-like tetramer with active sites facing a central pore
  7. 2055994Species Human (Homo sapiens) [TaxId:9606] [50547] (20 PDB entries)
  8. 2056042Domain d4mpwb_: 4mpw B: [270293]
    automated match to d1a0la_
    complexed with 2aj, act, cl, pge

Details for d4mpwb_

PDB Entry: 4mpw (more details), 1.95 Å

PDB Description: human beta-tryptase co-crystal structure with [(1,1,3,3- tetramethyldisiloxane-1,3-diyl)di-1-benzofuran-3,5-diyl]bis({4-[3- (aminomethyl)phenyl]piperidin-1-yl}methanone)
PDB Compounds: (B:) tryptase alpha/beta-1

SCOPe Domain Sequences for d4mpwb_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4mpwb_ b.47.1.2 (B:) beta-Tryptase {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d4mpwb_:

Click to download the PDB-style file with coordinates for d4mpwb_.
(The format of our PDB-style files is described here.)

Timeline for d4mpwb_: