Lineage for d4mpub_ (4mpu B:)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2055629Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. 2055630Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families) (S)
  5. 2055877Family b.47.1.2: Eukaryotic proteases [50514] (49 protein domains)
  6. 2055993Protein beta-Tryptase [50546] (1 species)
    ring-like tetramer with active sites facing a central pore
  7. 2055994Species Human (Homo sapiens) [TaxId:9606] [50547] (20 PDB entries)
  8. 2056008Domain d4mpub_: 4mpu B: [270291]
    automated match to d1a0la_
    complexed with mes, pg4, so4, x2a

Details for d4mpub_

PDB Entry: 4mpu (more details), 1.65 Å

PDB Description: human beta-tryptase co-crystal structure with (6s,8r)-n,n'-bis[3-({4- [3-(aminomethyl)phenyl]piperidin-1-yl}carbonyl)phenyl]-8-hydroxy-6- (1-hydroxycyclobutyl)-5,7-dioxaspiro[3.4]octane-6,8-dicarboxamide
PDB Compounds: (B:) tryptase alpha/beta-1

SCOPe Domain Sequences for d4mpub_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4mpub_ b.47.1.2 (B:) beta-Tryptase {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d4mpub_:

Click to download the PDB-style file with coordinates for d4mpub_.
(The format of our PDB-style files is described here.)

Timeline for d4mpub_: